C4BPA 抗体
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北京 101111
Quick Overview for C4BPA 抗体 (ABIN181109)
抗原
See all C4BPA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes complement component 4 binding protein (C4bp).
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产品特性
- Synonyms: C4BPA, C4BP, Proline-rich protein, PRP
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纯化方法
- Affinity Chromatography on Protein A.
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免疫原
- Native Human C4 binding protein. Genename: C4BP
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亚型
- IgG2b
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应用备注
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ELISA. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Borate buffered saline, pH 8.4 containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))
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别名
- C4b-Binding Protein alpha
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背景
- There are three variants of C4bp, composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.Synonyms: C4BP, C4BPA, PRP, Proline-rich protein
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基因ID
- 722
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UniProt
- P04003
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途径
- Complement System
抗原
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