ALIX 抗体
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北京 101111
Quick Overview for ALIX 抗体 (ABIN181090)
抗原
See all ALIX (PDCD6IP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises apoptotic-linked-gene-product 2 (ALG-2) interacting protein X (ALIX), a conserved adaptor protein which is ubiquitously expressed.
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产品特性
- Synonyms: PDCD6-interacting protein, ALG-2-interacting protein 1, Hp95, KIAA1375, Programmed celldeath 6-interacting protein
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Alix fusion protein.
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亚型
- IgG1
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应用备注
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ELISA. Western Blot. Immunoprecipitation. Immunofluorescence. Immunohistochemistry on Paraffin Sections: This product does not require proteindigestion pre-treatment of paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
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别名
- ALIX / PDCD6IP
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背景
- ALIX was originally reported to play a role in apoptosis but has recently been shown to be involved in other cellular mechanisms including endosomal sorting, endocytosis, viral budding and actin cytoskeleton assembly. ALG2 interacting protein X is a Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen. In case of infection, the HIV-1 virus directly takes advantage of its function for viral exocytosis and budding, via its interaction with HIV-1 p6 protein. It may play a role in the regulation of both apoptosis and cell proliferationSynonyms: ALG-2-interacting protein 1, Hp95, KIAA1375, PDCD6-interacting protein, Programmed cell death 6-interacting protein
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基因ID
- 10015
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UniProt
- Q8WUM4
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途径
- p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
抗原
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