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Interleukin 17a 抗体

The 大鼠 单克隆 anti-Interleukin 17a antibody is suitable to detect Interleukin 17a in samples from 小鼠. It has been validated for WB, FACS, EIA 和 IHC (p).
产品编号 ABIN181034
发货至: 中国
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Quick Overview for Interleukin 17a 抗体 (ABIN181034)

抗原

See all Interleukin 17a (IL17A) 抗体
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Interleukin 17a antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

TC11-18H10
  • 特异性

    This antibody recognizes Mouse Interleukin 17, a 32 kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family

    产品特性

    Synonyms: IL-17A, IL17, IL-17, CTLA8, CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8

    纯化方法

    Purified

    亚型

    IgG1
  • 应用备注

    Western Blot. Flow Cytometry. ELISA: Can be used in a sandwich ELISA with ABIN181031 as a detection antibody.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Borate buffered saline with no preservative or stabilizer

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Store the antibody in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    Interleukin-17A (IL17A)

    背景

    IL17, also known as CTLA8, is a T cell derived hematopoietic cytokine. It was originally cloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and a rat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts, the enhancement of surface expression of ICAM 1 in fibroblasts, activation of NF kappaB and costimulation of T cell proliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. The precursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 amino acids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 shows approximately 62.5 % amino acid homology to mouse IL17 and 58 % amino acid homology to rat IL17.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17

    基因ID

    16171

    UniProt

    Q62386
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