SOD1 抗体
Quick Overview for SOD1 抗体 (ABIN180961)
抗原
See all SOD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes Copper/Zinc Superoxide Dismutase (SOD). It does not cross react with immunoglobulins but does react weakly with Mn SOD.
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Human.
Species reactivity (tested):Bovine. -
产品特性
- Synonyms: SOD-1, CuZn-SOD, CuZnSOD, IPOA, ALS1, Superoxide dismutase [Cu-Zn]
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Superoxide dismutase enzyme prepared from bovine erythrocytes. Cells from immunisedmice were fused with cells of the mouse Sp-2/0-Ag14 myeloma cell line.
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亚型
- IgG1
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anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 1-154) antibody
SOD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) antibodyKO Validated SOD1 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (C-Term) antibodyKO Validated SOD1 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibodySOD1 适用: 人, 马 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 6-100) antibodySOD1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), FACS, IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibodySOD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibodySOD1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibody (APC)SOD1 适用: 兔 WB, IHC 宿主: 豚鼠 Polyclonal APC
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibodySOD1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibodySOD1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: This product does not require pre-treatmentof paraffin embedded sections e. g. trypsin or pronase prior to staining. This product doesnot require antigen retrieval using heat treatment methods prior to staining of paraffinsections. Recommended Positive Control: Human spleen and lymph node.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative and 0.1 % BSA as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
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别名
- Superoxide Dismutase 1 / SOD1
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背景
- Superoxide dismutases are ubiquitous metalloproteins that destroy oxygen-mediated free radicals, that are normally produced within the cells, which are toxic to biological systems. There are three forms of superoxide dismutase, including the Fe, mitochondrial (Mn) and the copper/zinc binding (Cu/Zn) form. The Cu/Zn form of SOD is utilised by most eukaryotic organisms. SOD Cu/Zn prevents oxygen-mediated free radical damage by catalysing the dismutation of the toxic superoxide radical to molecular oxygen and hydrogen peroxide. Superoxide dismutatses catalyzes the conversion of single electron reduced species of molecular oxygen to hydrogen peroxide and oxygen. Cu, Zn superoxide dismutase (SOD1) is widely distributed and comprises 90 % of total SOD. Mutations in SOD1 cause a form of familial ALS. Oxidative modifications and aggregation of SOD1 has been associated with Alzheimer's and Parkinson's disease.Synonyms: ALS1, CuZn-SOD, CuZnSOD, IPOA, SOD-1, Superoxide dismutase [Cu-Zn]
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基因ID
- 6647
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UniProt
- P00441
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途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis
抗原
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