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IDO1 抗体 (AA 78-184)

This anti-IDO1 antibody is a 小鼠 单克隆 antibody detecting IDO1 in WB 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN180889
发货至: 中国

Quick Overview for IDO1 抗体 (AA 78-184) (ABIN180889)

抗原

See all IDO1 抗体
IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

适用

  • 83
  • 31
  • 16
  • 9
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 78
  • 15
  • 1
  • 1
小鼠

克隆类型

  • 69
  • 26
  • 1
单克隆

标记

  • 67
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IDO1 antibody is un-conjugated

应用范围

  • 74
  • 37
  • 37
  • 23
  • 17
  • 16
  • 15
  • 14
  • 12
  • 12
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

10-01-14
  • 抗原表位

    • 16
    • 12
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 78-184

    特异性

    This Monoclonal antibody 10.1 recognizes Indoleamine-pyrrole 2,3-dioxygenase (IDO), an enzyme responsible for the catabolism of Tryptophan to N-Formlkynurenine and Kynurenine. In Western Blotting, it recognizes a 45 kDa band in IFN-gamma treated Human cell lines. This antibody recognizes a slightly lower Molecular Weight band in Mouse IDO compared to its Human counterpart.

    产品特性

    Synonyms: IDO1, IDO, INDO, Indoleamine 2, 3-dioxygenase 1, EC=1.13.11.52, 3-dioxygenase,Indoleamine-pyrrole 2

    纯化方法

    Purified

    免疫原

    Peptide corresponding to amino acids 78-184 of human IDO fused to GST

    亚型

    IgG3
  • 应用备注

    Western Blot. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

    别名

    IDO1 / INDO

    背景

    With the exception of tryptophan oxidase in hepatocytes, IDO is the only enzyme that degrades the amino acid tryptophan to kynurenine. Chlamydial pathogens require tryptophan for growth. IDO can lower available tryptophan in target cells leading to conversion of the pathogen to persistant forms, with significance in the progression to chronic infection with its associated pathological effects.Synonyms: 3-dioxygenase, 3-dioxygenase 1, EC=1.13.11.52, IDO, IDO1, INDO, Indoleamine 2, Indoleamine-pyrrole 2

    基因ID

    3620

    UniProt

    P14902

    途径

    Activated T Cell Proliferation
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