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Podoplanin 抗体

This anti-Podoplanin antibody is a 大鼠 单克隆 antibody detecting Podoplanin in WB, FACS, IP, IHC (p) 和 IHC (fro). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN180856
发货至: 中国

Quick Overview for Podoplanin 抗体 (ABIN180856)

抗原

See all Podoplanin (PDPN) 抗体
Podoplanin (PDPN)

适用

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宿主

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大鼠

克隆类型

  • 63
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  • 1
单克隆

标记

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This Podoplanin antibody is un-conjugated

应用范围

  • 91
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  • 36
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  • 24
  • 15
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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

NZ-1
  • 特异性

    The monoclonal antibody will detect Human Podoplanin on the surface of lymphatic endothelial cells and kidney podocytes. Therefore, it will be a useful tool to study lymphatic vessel density in and around Human tumors. Does not react with Mouse.

    产品特性

    Synonyms: Glycoprotein 36, PA2.26 antigen, T1-alpha, Aggrus, PDPN, GP36, PSEC0003, PSEC0025

    纯化方法

    Purified

    亚型

    IgG2a
  • 应用备注

    FACS (1/200). Western blot (>/= 1/200). Immunoprecipitation: 1/50. Immunostaining/Immunohistochemistry on Frozen and Paraffin Sections (1/200). Suitablefor Formalin-Fixed Paraffin Embedded Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in working aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • Martín-Villar, Fernández-Muñoz, Parsons, Yurrita, Megías, Pérez-Gómez, Jones, Quintanilla: "Podoplanin associates with CD44 to promote directional cell migration." in: Molecular biology of the cell, Vol. 21, Issue 24, pp. 4387-99, (2011) (PubMed).

  • 抗原

    Podoplanin (PDPN)

    别名

    Podoplanin

    背景

    Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a Mr 38,000 membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.Synonyms: Aggrus, GP36, Glycoprotein 36, PA2.26 antigen, PDPN, PSEC0003, PSEC0025, T1-alpha

    基因ID

    10630

    UniProt

    Q86YL7

    途径

    Dicarboxylic Acid Transport
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