CD74 抗体
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- 抗原 See all CD74 抗体
- CD74 (HLA-DR-gamma (CD74))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD74 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 特异性
- This antibody recognizes Human CD74, a type II transmembrane protein, which is also known as the MHC class II associated invariant chain. The Bu45 antibody recognizes 33, 35 and 41 kDa isoforms of CD74.
- 产品特性
- Synonyms: p33, DHLAG, HLA class II histocompatibility antigen gamma chain, HLA-DRantigens-associated invariant chain, Ia antigen-associated invariant chain
- 纯化方法
- Affinity chromatography on Protein G
- 免疫原
- B lymphoblastoid cell line HFB1. Spleen cells from immunised mice were fused with cells ofthe Ag8. 653 myeloma cell line. Genename: CD74
- 克隆位点
- Bu45
- 亚型
- IgG1
- Top Product
- Discover our top product CD74 Primary Antibody
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anti-HLA-DR-gamma (CD74) (AA 1-106) antibody
CD74 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 2D1B3 unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) (AA 78-222) antibodyCD74 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) (AA 64-205) antibodyCD74 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) (AA 1-106) antibodyCD74 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 2D1B11 unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 适用: 人, 小鼠, Baboon FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal LN-2 unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 适用: 人 WB, FACS, IF, IHC, IP, ICC 宿主: 小鼠 Monoclonal PIN-1 unconjugated
anti-HLA-DR-gamma (CD74) (AA 73-232) antibodyCD74 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-HLA-DR-gamma (CD74) (N-Term) antibodyCD74 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunoprecipitation. Immunohistochemistry on frozen sections. Flow Cytometry: 1/25 - 1/50,use 10 μL of the suggested working dilution to label 1x106 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0mg/mL
- 缓冲液
- PBS, pH 7.4, 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store at +4 °C or at -20 °C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- CD74 (HLA-DR-gamma (CD74))
- 别名
- CD74 (CD74 产品)
- 别名
- DHLAG antibody, HLADG antibody, II antibody, Ia-GAMMA antibody, CLIP antibody, Ii antibody, INVG34 antibody, Iclp-1 antibody, iclp1 antibody, wu:fb11f09 antibody, wu:fb12a01 antibody, wu:fb13d06 antibody, wu:fk94e07 antibody, Iclp-2 antibody, cd74 antibody, iclp2 antibody, zgc:123161 antibody, CD74 molecule antibody, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) antibody, CD74 molecule, major histocompatibility complex, class II invariant chain a antibody, CD74 molecule, major histocompatibility complex, class II invariant chain b antibody, CD74 antibody, Cd74 antibody, cd74a antibody, cd74b antibody
- 背景
- The CD74 Molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, dendritic cells and by various types of carcinoma. Expression of CD74 is primarily intracellular with moderate expression at the cell surface of B cells and monocytes. The Bu45 antibody binds to an epitope within the extracytoplasmic domain of the CD74 Molecule, which is distal from the C-terminus.Synonyms: DHLAG, HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain, p33
- 基因ID
- 972
- UniProt
- P04233
- 途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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