Complement C4c 抗体
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北京 101111
Quick Overview for Complement C4c 抗体 (ABIN1804101)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes complement component 4c (C4c). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. iC4b is further degraded into the inactive fragments C4d and C4c. C4c consists of two a-chain fragments, alpha 4 (13 kD) and alpha 3 (25 kD) linked to a beta chain through disulphide bridges and a gamma chain. It is expressed in the blood plasma. Binds both C4c and C4 and so is not suitable for all ELISA applications.
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纯化方法
- Protein A purified from ascites
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免疫原
- Purified human C4c.
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亚型
- IgG1
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anti-Complement Component C4c (C4c) (AA 19-333) antibody
C4c 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4c (C4c) (AA 19-333) antibodyC4c 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Complement Component C4c (C4c) (AA 680-756) antibodyC4c 适用: 人 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Approved: ELISA, Flo, IHC, IHC-Fr, IHC-P (10 μg/mL), WB
Usage: ELISA: Binds both C4c and C4 and so is not suitable for all ELISA applications. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Borate buffered saline, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Aliquot to avoid repeated freezing and thawing. Store undiluted.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
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- Complement C4c (C4c) (Complement Component C4c (C4c))
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别名
- Complement C4c
抗原
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