CCR4 抗体
Quick Overview for CCR4 抗体 (ABIN179723)
抗原
See all CCR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Anti-human CCR4
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纯化方法
- Protein G
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免疫原
- immunisation with human CCR4 peptide
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亚型
- IgG2a
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anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 201-300) antibody
CCR4 适用: 人, 大鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (N-Term) antibodyCCR4 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (Extracellular Domain) antibodyCCR4 适用: 人, 猴 ELISA, WB, FACS, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 309-360) antibodyCCR4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (Extracellular Domain) antibodyCCR4 适用: 人, 猴 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (N-Term) antibodyCCR4 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 17-39) antibodyCCR4 适用: 人 ELISA, WB, FACS, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 337-351) antibodyCCR4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 180-229) antibodyCCR4 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) antibodyCCR4 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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应用备注
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Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. -
说明
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Synonyms: CC chemokine receptor 4
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限制
- 仅限研究用
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浓度
- 2 mg/mL
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C
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储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
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别名
- CCR4
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背景
- CCR4 (CC chemokine receptor 4) molecule belongs to the rhodopsin family of G-protein-coupled receptors. Chemokine receptors are membrane bound molecules composed of 7-transmembrane domains and coupled to G-proteins. CCR4 binds the chemokines CCL17 (TARC) and CCL22 (MDC) and is highly expressed in most single-positive CD4(+) thymocytes especially in TH2- and regulatory T-cells. It plays a central role in T cell migration to the thymus, T cell maturation and education. CCR4 is often up-regulated in inflammation and cause conformational changes that trigger intracellular signaling pathways.
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UniProt
- P51679
抗原
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