ZYX 抗体 (AA 1-572)
Quick Overview for ZYX 抗体 (AA 1-572) (ABIN1742558)
抗原
See all ZYX 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-572
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原理
- Mouse anti-Zyxin IgG
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特异性
- Specific for zyxin.
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交叉反应 (详细)
- Reacts with: human (Q15942), rat, mouse (Q62523), hamster. Other species not tested yet.
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纯化方法
- purified IgG
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免疫原
- Recombinant protein corresponding to AA 1 to 572 from human Zyxin (UniProt Id: Q15942) Epitop AA 352 to 357 from human Zyxin (UniProt Id: Q15942)
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亚型
- IgG1
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应用备注
- WB:1 : 100 up to 1 : 2000 , IP:yes ICC:1 : 100, IHC:not tested yet IHC-P:1 : 200,
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.
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缓冲液
- PBS. Albumin and azide were added for stabilization.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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储存条件
- -20 °C,-80 °C,4 °C
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储存方法
- Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!
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: "Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin." in: Scientific reports, Vol. 6, pp. 23258, (2016) (PubMed).
: "Cell shape-dependent early responses of fibroblasts to cyclic strain." in: Biochimica et biophysica acta, Vol. 1833, Issue 12, pp. 3415-25, (2013) (PubMed).
: "Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7712-21, (2010) (PubMed).
: "Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis." in: Experimental cell research, Vol. 316, Issue 12, pp. 1925-34, (2010) (PubMed).
: "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." in: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3115-24, (2009) (PubMed).
: "mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes." in: American journal of physiology. Renal physiology, Vol. 296, Issue 2, pp. F418-26, (2009) (PubMed).
: "Targeted disruption of the mouse Lipoma Preferred Partner gene." in: Biochemical and biophysical research communications, Vol. 379, Issue 2, pp. 368-73, (2009) (PubMed).
: "Retrograde fluxes of focal adhesion proteins in response to cell migration and mechanical signals." in: Molecular biology of the cell, Vol. 18, Issue 11, pp. 4519-27, (2007) (PubMed).
: "TES is a novel focal adhesion protein with a role in cell spreading." in: Journal of cell science, Vol. 116, Issue Pt 5, pp. 897-906, (2003) (PubMed).
: "The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions." in: The Journal of cell biology, Vol. 161, Issue 1, pp. 33-9, (2003) (PubMed).
: "Zyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions." in: Molecular biology of the cell, Vol. 12, Issue 10, pp. 3103-13, (2001) (PubMed).
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: "Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin." in: Scientific reports, Vol. 6, pp. 23258, (2016) (PubMed).
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- ZYX (Zyxin (ZYX))
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别名
- Zyxin
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背景
- Zyxin is involved in the regulation of actin dynamics
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UniProt
- Q15942
抗原
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