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ZYX 抗体 (AA 1-572)

There are 11+ publications for this product available. The 小鼠 单克隆 anti-ZYX antibody is suitable to detect ZYX in samples from 人, 小鼠, 大鼠 和 Hamster. It has been validated for WB, IP, ICC 和 IHC (p).
产品编号 ABIN1742558
发货至: 中国
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Quick Overview for ZYX 抗体 (AA 1-572) (ABIN1742558)

抗原

See all ZYX 抗体
ZYX (Zyxin (ZYX))

适用

  • 72
  • 33
  • 16
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠, Hamster

宿主

  • 61
  • 10
  • 1
小鼠

克隆类型

  • 45
  • 26
单克隆

标记

  • 36
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
This ZYX antibody is un-conjugated

应用范围

  • 50
  • 25
  • 23
  • 19
  • 17
  • 14
  • 11
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

164D4
  • 抗原表位

    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-572

    原理

    Mouse anti-Zyxin IgG

    特异性

    Specific for zyxin.

    交叉反应 (详细)

    Reacts with: human (Q15942), rat, mouse (Q62523), hamster. Other species not tested yet.

    纯化方法

    purified IgG

    免疫原

    Recombinant protein corresponding to AA 1 to 572 from human Zyxin (UniProt Id: Q15942) Epitop AA 352 to 357 from human Zyxin (UniProt Id: Q15942)

    亚型

    IgG1
  • 应用备注

    WB:1 : 100 up to 1 : 2000 , IP:yes ICC:1 : 100, IHC:not tested yet IHC-P:1 : 200,

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

    缓冲液

    PBS. Albumin and azide were added for stabilization.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,-80 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!
  • Missirlis, Haraszti, Scheele, Wiegand, Diaz, Neubauer, Rechenmacher, Kessler, Spatz: "Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin." in: Scientific reports, Vol. 6, pp. 23258, (2016) (PubMed).

    Gadhari, Charnley, Marelli, Brugger, Chiquet: "Cell shape-dependent early responses of fibroblasts to cyclic strain." in: Biochimica et biophysica acta, Vol. 1833, Issue 12, pp. 3415-25, (2013) (PubMed).

    Delaroche, Cantrelle, Subra, Van Heijenoort, Guittet, Jiao, Blanchoin, Chassaing, Lavielle, Auclair, Sagan: "Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7712-21, (2010) (PubMed).

    Low, Mukhina, Srinivas, Ng, Murata-Hori: "Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis." in: Experimental cell research, Vol. 316, Issue 12, pp. 1925-34, (2010) (PubMed).

    Mori, Nakagami, Koibuchi, Miura, Takami, Koriyama, Hayashi, Sabe, Mochizuki, Morishita, Kaneda: "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." in: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3115-24, (2009) (PubMed).

    Vollenbröker, George, Wolfgart, Saleem, Pavenstädt, Weide: "mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes." in: American journal of physiology. Renal physiology, Vol. 296, Issue 2, pp. F418-26, (2009) (PubMed).

    Vervenne, Crombez, Delvaux, Janssens, Van de Ven, Petit: "Targeted disruption of the mouse Lipoma Preferred Partner gene." in: Biochemical and biophysical research communications, Vol. 379, Issue 2, pp. 368-73, (2009) (PubMed).

    Guo, Wang: "Retrograde fluxes of focal adhesion proteins in response to cell migration and mechanical signals." in: Molecular biology of the cell, Vol. 18, Issue 11, pp. 4519-27, (2007) (PubMed).

    Coutts, MacKenzie, Griffith, Black: "TES is a novel focal adhesion protein with a role in cell spreading." in: Journal of cell science, Vol. 116, Issue Pt 5, pp. 897-906, (2003) (PubMed).

    Garvalov, Higgins, Sutherland, Zettl, Scaplehorn, Köcher, Piddini, Griffiths, Way: "The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions." in: The Journal of cell biology, Vol. 161, Issue 1, pp. 33-9, (2003) (PubMed).

    Rottner, Krause, Gimona, Small, Wehland: "Zyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions." in: Molecular biology of the cell, Vol. 12, Issue 10, pp. 3103-13, (2001) (PubMed).

  • 抗原

    ZYX (Zyxin (ZYX))

    别名

    Zyxin

    背景

    Zyxin is involved in the regulation of actin dynamics

    UniProt

    Q15942
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