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CHRNB1 抗体

This 大鼠 单克隆 antibody specifically detects CHRNB1 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠. It has been mentioned in 3+ publications
产品编号 ABIN1742452
发货至: 中国
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Quick Overview for CHRNB1 抗体 (ABIN1742452)

抗原

See all CHRNB1 抗体
CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

适用

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人, 小鼠, 大鼠

宿主

  • 23
  • 1
  • 1
大鼠

克隆类型

  • 23
  • 2
单克隆

标记

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This CHRNB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

2-1-155
  • 原理

    Rat anti-m-AChR-2 IgG

    特异性

    Specific for muscarinic acetylcholine receptor 2.

    交叉反应 (详细)

    Reacts with: human (P08172), rat (P10980), mouse (Q9ERZ4). Other species not tested yet.

    纯化方法

    purified IgG

    免疫原

    207 to 388 from human m-AChR-2 (UniProt Id: P08172) Epitop AA 207 to 388 from human m-AChR-2 (UniProt Id: P08172)

    亚型

    IgG1
  • 应用备注

    WB:1 : 1000 , IP:not tested yet ICC:not tested yet IHC:1 : 100, IHC-P:not tested yet

    说明

    This antibody detects also higher molecular weight bands, depending on the glycosilation state of the protein. The protein tends to aggregate after boiling, making it necessary to run SDS-PAGE with non-boiled samples.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

    缓冲液

    PBS.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,-80 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!
  • Duttaroy, Gomeza, Gan, Siddiqui, Basile, Harman, Smith, Felder, Levey, Wess: "Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice." in: Molecular pharmacology, Vol. 62, Issue 5, pp. 1084-93, (2002) (PubMed).

    Bernard, Laribi, Levey, Bloch: "Subcellular redistribution of m2 muscarinic acetylcholine receptors in striatal interneurons in vivo after acute cholinergic stimulation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 18, Issue 23, pp. 10207-18, (1998) (PubMed).

    Levey, Edmunds, Hersch, Wiley, Heilman: "Light and electron microscopic study of m2 muscarinic acetylcholine receptor in the basal forebrain of the rat." in: The Journal of comparative neurology, Vol. 351, Issue 3, pp. 339-56, (1995) (PubMed).

  • 抗原

    CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

    别名

    AChR-2

    背景

    Synonyms: m-AChR-2, Acetylcholine Receptor 2, Chrm2, muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M2, Cholinergic receptor muscarinic 2, spinal cord, striatum

    Antigen Information: m-AChR-2 is a G protein-coupled acetylcholine receptor

    UniProt

    P08172

    途径

    Synaptic Membrane
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