CHRNB1 抗体
Quick Overview for CHRNB1 抗体 (ABIN1742452)
抗原
See all CHRNB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Rat anti-m-AChR-2 IgG
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特异性
- Specific for muscarinic acetylcholine receptor 2.
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交叉反应 (详细)
- Reacts with: human (P08172), rat (P10980), mouse (Q9ERZ4). Other species not tested yet.
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纯化方法
- purified IgG
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免疫原
- 207 to 388 from human m-AChR-2 (UniProt Id: P08172) Epitop AA 207 to 388 from human m-AChR-2 (UniProt Id: P08172)
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亚型
- IgG1
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应用备注
- WB:1 : 1000 , IP:not tested yet ICC:not tested yet IHC:1 : 100, IHC-P:not tested yet
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说明
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This antibody detects also higher molecular weight bands, depending on the glycosilation state of the protein. The protein tends to aggregate after boiling, making it necessary to run SDS-PAGE with non-boiled samples.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.
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缓冲液
- PBS.
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注意事项
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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储存条件
- -20 °C,-80 °C,4 °C
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储存方法
- Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!
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: "Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice." in: Molecular pharmacology, Vol. 62, Issue 5, pp. 1084-93, (2002) (PubMed).
: "Subcellular redistribution of m2 muscarinic acetylcholine receptors in striatal interneurons in vivo after acute cholinergic stimulation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 18, Issue 23, pp. 10207-18, (1998) (PubMed).
: "Light and electron microscopic study of m2 muscarinic acetylcholine receptor in the basal forebrain of the rat." in: The Journal of comparative neurology, Vol. 351, Issue 3, pp. 339-56, (1995) (PubMed).
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: "Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice." in: Molecular pharmacology, Vol. 62, Issue 5, pp. 1084-93, (2002) (PubMed).
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- CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))
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别名
- AChR-2
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背景
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Synonyms: m-AChR-2, Acetylcholine Receptor 2, Chrm2, muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M2, Cholinergic receptor muscarinic 2, spinal cord, striatum
Antigen Information: m-AChR-2 is a G protein-coupled acetylcholine receptor
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UniProt
- P08172
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途径
- Synaptic Membrane
抗原
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