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LRRC32 抗体 (AA 296-308)

Cited in 3+ publications. This anti-LRRC32 antibody is a 小鼠 单克隆 antibody detecting LRRC32 in FACS. Suitable for 人.
产品编号 ABIN1742450
发货至: 中国
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Quick Overview for LRRC32 抗体 (AA 296-308) (ABIN1742450)

抗原

See all LRRC32 抗体
LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

适用

  • 30
  • 11
  • 9
  • 1

宿主

  • 22
  • 16
  • 1
  • 1
小鼠

克隆类型

  • 23
  • 17
单克隆

标记

  • 20
  • 8
  • 5
  • 3
  • 2
  • 1
  • 1
This LRRC32 antibody is un-conjugated

应用范围

  • 17
  • 16
  • 14
  • 5
  • 2
  • 2
  • 2
  • 1
Flow Cytometry (FACS)

克隆位点

272G6
  • 抗原表位

    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 296-308

    原理

    Mouse anti-GARP IgG

    特异性

    Specific for GARP.

    交叉反应 (详细)

    Reacts with: human (Q14392). Other species not tested yet.

    纯化方法

    purified IgG

    免疫原

    Synthetic peptide corresponding to AA 296 to 308 from human GARP (UniProt Id: Q14392)

    亚型

    IgG3
  • 应用备注

    WB:not recommended IP:not tested yet ICC:not tested yet IHC:not tested yet IHC-P:not tested yet FACS:yes

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

    缓冲液

    PBS. Azide was added before lyophilization.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,-80 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!
  • Cuende, Liénart, Dedobbeleer, van der Woning, De Boeck, Stockis, Huygens, Colau, Somja, Delvenne, Hannon, Baron, Dumoutier, Renauld, De Haard, Saunders, Coulie, Lucas: "Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo." in: Science translational medicine, Vol. 7, Issue 284, pp. 284ra56, (2015) (PubMed).

    Rappl, Pabst, Riemann, Schmidt, Wickenhauser, Schütte, Hombach, Seliger, Grohé, Abken: "Regulatory T cells with reduced repressor capacities are extensively amplified in pulmonary sarcoid lesions and sustain granuloma formation." in: Clinical immunology (Orlando, Fla.), Vol. 140, Issue 1, pp. 71-83, (2011) (PubMed).

    Probst-Kepper, Geffers, Kröger, Viegas, Erck, Hecht, Lünsdorf, Roubin, Moharregh-Khiabani, Wagner, Ocklenburg, Jeron, Garritsen, Arstila, Kekäläinen, Balling, Hauser, Buer, Weiss: "GARP: a key receptor controlling FOXP3 in human regulatory T cells." in: Journal of cellular and molecular medicine, Vol. 13, Issue 9B, pp. 3343-57, (2010) (PubMed).

  • 抗原

    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

    别名

    GARP

    背景

    Synonyms: LRRC 32, CD 109

    Antigen Information: GARP is an orphan receptor on Treg-cells

    UniProt

    Q14392

    途径

    Activated T Cell Proliferation
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