LRRC32 抗体 (AA 296-308)
(3 references)Quick Overview for LRRC32 抗体 (AA 296-308) (ABIN1742450)
抗原
See all LRRC32 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 296-308
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特异性
- Specific for GARP.
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纯化方法
- purified IgG. Azide was added before lyophilization.
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免疫原
- Synthetic peptide (aa 296-308 of human GARP) coupled to KLH via N-terminal added cysteine.
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亚型
- IgG3
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anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 162-405) antibody
LRRC32 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 234-260) antibodyLRRC32 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 234-260) antibodyLRRC32 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB18218 unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 400-643) antibodyLRRC32 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) antibodyLRRC32 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal GARP5 unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 250-300) antibodyLRRC32 适用: 人, 小鼠, 大鼠, 猴 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 301-500) antibodyLRRC32 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 23-612) antibodyLRRC32 适用: 人 WB 宿主: 小鼠 Monoclonal 50G10 unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 240-269) antibodyLRRC32 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: not recommended
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
FACS: 1 : 100 up to 1 : 1000 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 100 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
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缓冲液
- PBS, 0.02% sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not store diluted antibody solutions unless you add detergent or carrier proteins such as goat serum, BSA or others. IgG sticks to glass and plastic. Any IgG solution below 0.1 mg/mL protein will quickly adsorb and denature and thus loose activity! Repetitive freeze-thawing of dilute purified IgG is almost certain to lead to substantial losses.
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储存条件
- -20 °C
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储存方法
- Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
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: "Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo." in: Science translational medicine, Vol. 7, Issue 284, pp. 284ra56, (2015) (PubMed).
: "Regulatory T cells with reduced repressor capacities are extensively amplified in pulmonary sarcoid lesions and sustain granuloma formation." in: Clinical immunology (Orlando, Fla.), Vol. 140, Issue 1, pp. 71-83, (2011) (PubMed).
: "GARP: a key receptor controlling FOXP3 in human regulatory T cells." in: Journal of cellular and molecular medicine, Vol. 13, Issue 9B, pp. 3343-57, (2010) (PubMed).
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: "Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo." in: Science translational medicine, Vol. 7, Issue 284, pp. 284ra56, (2015) (PubMed).
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- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
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别名
- GARP
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背景
- Synonyms: LRRC 32
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途径
- Activated T Cell Proliferation
抗原
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