LRRC32 抗体 (AA 296-308)
Quick Overview for LRRC32 抗体 (AA 296-308) (ABIN1742450)
抗原
See all LRRC32 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 296-308
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原理
- Mouse anti-GARP IgG
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特异性
- Specific for GARP.
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交叉反应 (详细)
- Reacts with: human (Q14392). Other species not tested yet.
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纯化方法
- purified IgG
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免疫原
- Synthetic peptide corresponding to AA 296 to 308 from human GARP (UniProt Id: Q14392)
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亚型
- IgG3
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应用备注
- WB:not recommended IP:not tested yet ICC:not tested yet IHC:not tested yet IHC-P:not tested yet FACS:yes
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.
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缓冲液
- PBS. Azide was added before lyophilization.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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储存条件
- -20 °C,-80 °C,4 °C
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储存方法
- Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!
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: "Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo." in: Science translational medicine, Vol. 7, Issue 284, pp. 284ra56, (2015) (PubMed).
: "Regulatory T cells with reduced repressor capacities are extensively amplified in pulmonary sarcoid lesions and sustain granuloma formation." in: Clinical immunology (Orlando, Fla.), Vol. 140, Issue 1, pp. 71-83, (2011) (PubMed).
: "GARP: a key receptor controlling FOXP3 in human regulatory T cells." in: Journal of cellular and molecular medicine, Vol. 13, Issue 9B, pp. 3343-57, (2010) (PubMed).
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: "Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo." in: Science translational medicine, Vol. 7, Issue 284, pp. 284ra56, (2015) (PubMed).
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- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
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别名
- GARP
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背景
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Synonyms: LRRC 32, CD 109
Antigen Information: GARP is an orphan receptor on Treg-cells
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UniProt
- Q14392
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途径
- Activated T Cell Proliferation
抗原
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