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Abeta 38/40/42 (AA 1-16), (AA 4-16) 抗体

This anti- antibody is a 小鼠 单克隆 antibody detecting in IHC, WB 和 ELISA. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1742437
发货至: 中国

Quick Overview for Abeta 38/40/42 (AA 1-16), (AA 4-16) 抗体 (ABIN1742437)

抗原

Abeta 38/40/42

适用

人, 小鼠

宿主

  • 2
小鼠

克隆类型

  • 2
单克隆

标记

  • 1
  • 1
非结合性

应用范围

Immunohistochemistry (IHC), Western Blotting (WB), ELISA

克隆位点

NT78
  • 抗原表位

    • 2
    • 1
    • 1
    AA 1-16, AA 4-16

    特异性

    Specific for Abeta 38, 40, 42.

    免疫原

    Synthetic peptide (aa 1-16) of abeta peptides 38, 40, 42 coupled to key-hole limpet hemocyanin via an added C-terminal cysteine residue. Epitope aa 4-16

    亚型

    IgG2b
  • 应用备注

    WB: 1:500 up to 1:1000 (ECL detection), IHC: 1:500, , ; unlabeled only,

    说明

    ELISA: Suitable as capture antibody for sandwich-ELISA as detector antibody (protocol for sandwich-ELISA).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 100µl H2O to get a 1mg/ml solution in PBS.

    缓冲液

    PBS. Azide was added before lyophilization.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C

    储存方法

    Reconstitute and aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized.
  • Jawhar, Wirths, Schilling, Graubner, Demuth, Bayer et al.: "Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in ..." in: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4454-60, (2011) (PubMed).

    Wirths, Erck, Martens, Harmeier, Geumann, Jawhar, Kumar, Multhaup, Walter, Ingelsson, Degerman-Gunnarsson, Kalimo, Huitinga, Lannfelt, Bayer: "Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis." in: The Journal of biological chemistry, Vol. 285, Issue 53, pp. 41517-24, (2010) (PubMed).

  • 抗原

    Abeta 38/40/42
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