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TNC 抗体 (AA 23-2210)

Cited in 5+ publications. This 大鼠 单克隆 anti-TNC antibody (Clone 578) specifically detects TNC in WB, IHC, IHC (p) 和 ICC. The antibody is reactive with 大鼠 和 小鼠 samples.
产品编号 ABIN1742432
发货至: 中国
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Quick Overview for TNC 抗体 (AA 23-2210) (ABIN1742432)

抗原

See all TNC 抗体
TNC (Tenascin C (TNC))

适用

  • 115
  • 44
  • 43
  • 15
  • 2
  • 2
  • 1
  • 1
大鼠, 小鼠

宿主

  • 89
  • 49
  • 2
  • 1
  • 1
大鼠

克隆类型

  • 75
  • 67
单克隆

标记

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  • 13
  • 8
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  • 3
  • 3
  • 3
  • 3
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  • 3
  • 3
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  • 2
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  • 1
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This TNC antibody is un-conjugated

应用范围

  • 77
  • 49
  • 28
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  • 11
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  • 10
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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

克隆位点

578
  • 抗原表位

    • 15
    • 15
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    • 1
    AA 23-2210

    原理

    Rat anti-Tenascin-C supernatant

    特异性

    Specific for tenascin-C splice variants carrying the FNIII D domain.

    交叉反应 (详细)

    Reacts with: rat, mouse (Q80YX1). Other species not tested yet.

    纯化方法

    hybridoma supernatant

    免疫原

    Recombinant protein corresponding to AA 23 to 2210 from mouse Tenascin-C (UniProt Id: Q80YX1) Epitop AA 1082 to 1510 from mouse Tenascin-C (UniProt Id: Q80YX1)

    亚型

    IgG2a
  • 应用备注

    WB:1 : 500 up to 1 : 1000 , IP:not tested yet ICC:1 : 100 up to 1 : 500, IHC:1 : 500, IHC-P:1 : 500 up to 1 : 1000,

    说明

    Tenascin-C variants detected by this antibody are downregulated during development and hardly detectable in adult animals

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
  • Siddiqui, Horvat-Bröcker, Faissner: "The glia-derived extracellular matrix glycoprotein tenascin-C promotes embryonic and postnatal retina axon outgrowth via the alternatively spliced fibronectin type III domain TNfnD." in: Neuron glia biology, Vol. 4, Issue 4, pp. 271-83, (2010) (PubMed).

    Rigato, Garwood, Calco, Heck, Faivre-Sarrailh, Faissner: "Tenascin-C promotes neurite outgrowth of embryonic hippocampal neurons through the alternatively spliced fibronectin type III BD domains via activation of the cell adhesion molecule F3/contactin." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 15, pp. 6596-609, (2002) (PubMed).

    Bartsch, Bartsch, Dörries, Faissner, Weller, Ekblom, Schachner: "Expression of tenascin in the developing and adult cerebellar cortex." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 12, Issue 3, pp. 736-49, (1992) (PubMed).

    Stern, Norris, Bronner-Fraser, Carlson, Faissner, Keynes, Schachner: "J1/tenascin-related molecules are not responsible for the segmented pattern of neural crest cells or motor axons in the chick embryo." in: Development (Cambridge, England), Vol. 107, Issue 2, pp. 309-19, (1990) (PubMed).

    Gatchalian, Schachner, Sanes: "Fibroblasts that proliferate near denervated synaptic sites in skeletal muscle synthesize the adhesive molecules tenascin(J1), N-CAM, fibronectin, and a heparan sulfate proteoglycan." in: The Journal of cell biology, Vol. 108, Issue 5, pp. 1873-90, (1989) (PubMed).

  • 抗原

    TNC (Tenascin C (TNC))

    别名

    Tenascin-C

    背景

    Synonyms: TN-C, TNC, J1-200/220, Hexabrachion, Cell Adhesion Proteins

    Antigen Information: Tenascin-C is a multidomain adhesion molecule

    UniProt

    Q80YX1

    途径

    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
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