MFN2 抗体 (AA 370-600) (Atto 390)
Quick Overview for MFN2 抗体 (AA 370-600) (Atto 390) (ABIN1741234)
抗原
See all MFN2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 370-600
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特异性
- Detects ~90 kDa. No cross-reactivity against Mitofusin-1.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2. Rat: 97% identity (226/231 amino acids identical). Human: 92% identity (214/231 amino acids identical) ~55% identity with Mitofusin-1.
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亚型
- IgG2a
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anti-Mitofusin 2 (MFN2) (AA 661-757) antibody
MFN2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-Mitofusin 2 (MFN2) (AA 1-120) antibodyMFN2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 500-600) antibodyMFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 687-757) antibodyMFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 447-476) antibodyMFN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (N-Term) antibodyMFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibodyMFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (PE)MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 PE
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (PerCP)MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 PerCP
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (APC)MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 APC
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应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN1741234 was sufficient for detection of Mitofusin-2 in 20 μg of mouse cardiac mitochondrial lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- MFN2 (Mitofusin 2 (MFN2))
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别名
- Mitofusin 2
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背景
- Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression.
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基因ID
- 170731
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NCBI登录号
- NP_573464
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UniProt
- Q80U63
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途径
- Skeletal Muscle Fiber Development
抗原
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