RAD17 抗体 (N-Term)
Quick Overview for RAD17 抗体 (N-Term) (ABIN1738687)
抗原
See all RAD17 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- Reacts with human Rad17
-
纯化方法
- Purified
-
免疫原
- Synthetic peptide made to a N-terminal region of human RAD17.
-
亚型
- IgG
-
-
-
-
应用备注
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/1 000 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, Sodium azide 0.01 %
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
-
有效期
- 6 months
-
-
- RAD17
-
别名
- Rad17
-
背景
- Signals originating from damaged DNA activate checkpoint pathways and target the mitotic apparatus via a number a distinct mechanisms.These checkpoints link damage to DNA with the components of the cell cycle through signal transduction systems. In mammals, five genes have been identified as components of DNA damage-induced checkpoint pathways: ATM, p53, p21/WAF1/CIP1, hCHK1, and 14-3-3sigma.When overexpressed in mammalian cells, hRAD17 activates p53 and causes an accumulation of G1 phase cells, suggesting an involvement of the hRAD17 gene in this checkpoint pathway.
抗原
-