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PARK7/DJ1 抗体 (N-Term)

PARK7 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1737863
发货至: 中国
  • 抗原 See all PARK7/DJ1 (PARK7) 抗体
    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
    抗原表位
    • 21
    • 16
    • 11
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 167-189, N-Term
    适用
    • 88
    • 69
    • 50
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 94
    • 15
    • 2
    • 1
    克隆类型
    • 90
    • 22
    多克隆
    标记
    • 66
    • 13
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PARK7/DJ1 antibody is un-conjugated
    应用范围
    • 92
    • 44
    • 30
    • 29
    • 24
    • 20
    • 17
    • 14
    • 13
    • 13
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Reacts with human and mouse PARK7. Sequence homology to mouse and rat DJ-1 is 82 % .
    纯化方法
    Purified
    免疫原
    Synthetic peptide corresponding to amino acids 167-189 (AIVEALNGKEVAAQVKAPLVLKD) of human PARK7 conjugated to KLH at the N-terminus.
    亚型
    IgG
    Top Product
    Discover our top product PARK7 Primary Antibody
  • 应用备注
    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    WB1:500

    Positive control: HEK293 cell lysate or mouse brain tissue lysate
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.4,
    注意事项
    Dilute in PBS or medium which is identical to that used in the assay system.
    储存条件
    4 °C/-20 °C
    储存方法
    Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
    有效期
    6 months
  • 抗原
    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
    别名
    Park7 (PARK7 产品)
    别名
    DJ-1 antibody, DJ1 antibody, CAP1 antibody, Dj1 antibody, SP22 antibody, dj1 antibody, zgc:103725 antibody, park7b antibody, park7 antibody, park7a antibody, Parkinsonism associated deglycase antibody, Parkinson disease (autosomal recessive, early onset) 7 antibody, parkinson protein 7 antibody, parkinson protein 7 S homeolog antibody, parkinson protein 7 L homeolog antibody, PARK7 antibody, Park7 antibody, park7 antibody, park7.S antibody, park7.L antibody
    背景
    Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.

    Protein DJ-1 Oncogene DJ1 Parkinson disease protein 7 Gene name: PARK7
    基因ID
    11315
    UniProt
    Q99497
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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