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PARK7/DJ1 抗体 (N-Term)

PARK7 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB8160 unconjugated
产品编号 ABIN390371
发货至: 中国
  • 抗原 See all PARK7/DJ1 (PARK7) 抗体
    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
    抗原表位
    • 21
    • 16
    • 11
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 92
    • 70
    • 51
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 98
    • 15
    • 2
    • 1
    克隆类型
    • 93
    • 23
    多克隆
    标记
    • 70
    • 13
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PARK7/DJ1 antibody is un-conjugated
    应用范围
    • 96
    • 44
    • 31
    • 29
    • 26
    • 20
    • 19
    • 15
    • 14
    • 13
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    预测反应
    B, Zf
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This DJ-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DJ-1.
    克隆位点
    RB8160
    亚型
    Ig Fraction
    Top Product
    Discover our top product PARK7 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:2000. WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
    别名
    DJ-1 (PARK7 产品)
    别名
    DJ-1 antibody, DJ1 antibody, CAP1 antibody, Dj1 antibody, SP22 antibody, dj1 antibody, zgc:103725 antibody, park7b antibody, park7 antibody, park7a antibody, Parkinsonism associated deglycase antibody, Parkinson disease (autosomal recessive, early onset) 7 antibody, parkinson protein 7 antibody, parkinson protein 7 S homeolog antibody, parkinson protein 7 L homeolog antibody, PARK7 antibody, Park7 antibody, park7 antibody, park7.S antibody, park7.L antibody
    背景
    Park 7 acts as positive regulator of androgen receptor-dependent transcription, and may function as redox-sensitive chaperone and as sensor for oxidative stress, as well as preventing aggregation of SNCA. This protein has been shown to protect neurons against oxidative stress and cell death, and to play a role in fertilization. Park7 is detected in tau inclusions in brains from neurodegenerative disease patients, and is generally highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, with detectable levels in placenta, brain, astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Defects in Park7 are the cause of autosomal recessive early-onset Parkinson disease 7 (PARK7), a form of Parkinson disease characterized by onset before 40 years, slow progression and initial good response to levodopa.
    分子量
    19891
    基因ID
    11315
    NCBI登录号
    NP_001116849, NP_009193
    UniProt
    Q99497
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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