PARK7/DJ1 抗体 (N-Term)
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Quick Overview for PARK7/DJ1 抗体 (N-Term) (ABIN1737863)
抗原
See all PARK7/DJ1 (PARK7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 167-189, N-Term
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特异性
- Reacts with human and mouse PARK7. Sequence homology to mouse and rat DJ-1 is 82 % .
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纯化方法
- Purified
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免疫原
- Synthetic peptide corresponding to amino acids 167-189 (AIVEALNGKEVAAQVKAPLVLKD) of human PARK7 conjugated to KLH at the N-terminus.
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亚型
- IgG
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB1:500
Positive control: HEK293 cell lysate or mouse brain tissue lysate -
限制
- 仅限研究用
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缓冲液
- PBS, pH 7.4,
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注意事项
- Dilute in PBS or medium which is identical to that used in the assay system.
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储存条件
- 4 °C/-20 °C
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储存方法
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
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有效期
- 6 months
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- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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别名
- Park7
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背景
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Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.
Protein DJ-1 Oncogene DJ1 Parkinson disease protein 7 Gene name: PARK7 -
基因ID
- 11315
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UniProt
- Q99497
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
抗原
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