Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only : WB1:500
Positive control: HEK293 cell lysate or mouse brain tissue lysate
限制
仅限研究用
缓冲液
PBS, pH 7.4,
注意事项
Dilute in PBS or medium which is identical to that used in the assay system.
储存条件
4 °C/-20 °C
储存方法
Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
有效期
6 months
抗原
PARK7/DJ1 (PARK7)
(Parkinson Protein 7 (PARK7))
别名
Park7
背景
Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.
Protein DJ-1 Oncogene DJ1 Parkinson disease protein 7 Gene name: PARK7