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Amyloid Fibrils 抗体

The 兔 多克隆 anti-Amyloid Fibrils antibody is suitable to detect Amyloid Fibrils in samples from 人, 小鼠 和 大鼠. It has been validated for WB, DB, ELISA 和 IHC.
产品编号 ABIN1731752
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Amyloid Fibrils 抗体 (ABIN1731752)

抗原

Amyloid Fibrils

适用

人, 小鼠, 大鼠

宿主

  • 5

克隆类型

  • 5
多克隆

标记

  • 5
非结合性

应用范围

  • 5
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Dot Blot (DB), ELISA, Immunohistochemistry (IHC)
  • 特异性

    Reacts withepitopes common to many human amyloid fibrils and fibrillar oligomers but not prefibrillar oligomers or natively folded proteins. Predicted to recognize mouse and rat based on sequence homology.

    纯化方法

    Purified

    免疫原

    Fibrils prepared from human Abeta42 peptide

    亚型

    IgG
  • 应用备注

    Working dilution: Optimal dilutions should be determined by the end user.
    The following are guidelines only:
    WB1 -2 μg/mL DB0.5 - 1 μg/mL IHC1 -5 μg/mL ELISA1 - 10 μg/mL with amyloid fibril-containing samples on the solid phase.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS pH 7.0, 50 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Dilute in PBS or medium which is identical to that used in the assay system.

    储存条件

    -20 °C

    储存方法

    This product is stable for at least 1 year at -20°C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.
  • 抗原

    Amyloid Fibrils

    背景

    Amyloid monomeric proteins can oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibers.
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