GABBR2 抗体 (AA 319-483)
Quick Overview for GABBR2 抗体 (AA 319-483) (ABIN1724937)
抗原
See all GABBR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 319-483
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原理
- GABBR2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. Coli.
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亚型
- IgG2a
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应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." in: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).
: "
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GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." in: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).
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- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
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别名
- GABBR2
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背景
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The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
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分子量
- 105.8 kDa
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基因ID
- 9568
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UniProt
- O75899
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途径
- cAMP Metabolic Process
抗原
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