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Transferrin Receptor 抗体 (AA 608-727)

Name: Transferrin Receptor 抗体 (AA 608-727)
Brand: antibodies-online
SKU: ABIN1724899
Availability: OutOfStock

This anti-Transferrin Receptor antibody is a 小鼠单克隆 antibody detecting Transferrin Receptor in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠和猴. This Primary Antibody has been cited in 2+ publications.

Western blot analysis using TFRC mouse mAb against Jurkat (1), Hela (2), K562 (3), Cos7 (4), MCF-7 (5), PC-12 (6), NIH/3T3 (7), HEK293 (8), RAJI (9) cell lysate. (Transferrin Receptor 抗体 (AA 608-727))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Transferrin Receptor 抗体 (AA 608-727))

ELISA

Western blot analysis using TFRC mAb against human TFRC recombinant protein. (Transferrin Receptor 抗体 (AA 608-727))

Western blot analysis using TFRC mAb against HEK293 (1) and TFRC (AA: 608-727)-hIgGFc transfected HEK293 (2) cell lysate. (Transferrin Receptor 抗体 (AA 608-727))

4 images

(2 references)

产品编号 ABIN1724899

发货至: 中国

Quick Overview for Transferrin Receptor 抗体 (AA 608-727) (ABIN1724899)

抗原

See all Transferrin Receptor (TFRC) 抗体

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

人, 小鼠, 大鼠, 猴

宿主

小鼠

克隆类型

单克隆

标记

This Transferrin Receptor antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA

克隆位点

1A1B2

Discover our top product TFRC Primary Antibody

抗原表位
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AA 608-727

原理

TFRC Antibody

纯化方法

Purified antibody

免疫原

Purified recombinant fragment of human TFRC (AA: 608-727) expressed in E. Coli.

亚型

IgG1
anti-Transferrin Receptor (p90, CD71) (TFRC) antibody
TFRC 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal MEM-75 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 578-765) antibody
TFRC 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) antibody
TFRC 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 1-140) antibody
TFRC 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 68-168) antibody
TFRC 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1E6 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) antibody (Biotin)
TFRC 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal MEM-75 Biotin

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 621-720) antibody
TFRC 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibody
TFRC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 572-757) antibody
TFRC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibody
TFRC 适用: 人 IHC 宿主: 小鼠 Monoclonal C1 unconjugated

应用备注

ELISA: 1/10000

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Płoszyńska, Ruckemann-Dziurdzińska, Jóźwik, Mikosik, Lisowska, Balcerska, Witkowski: "Cytometric evaluation of transferrin receptor 1 (CD71) in childhood acute lymphoblastic leukemia." in: Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society, Vol. 50, Issue 2, pp. 304-11, (2012) (PubMed).

Jian, Yang, Huang: "Src regulates Tyr(20) phosphorylation of transferrin receptor-1 and potentiates breast cancer cell survival." in: The Journal of biological chemistry, Vol. 286, Issue 41, pp. 35708-15, (2011) (PubMed).
抗原

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

别名

TFRC

背景

Transferrin receptor is a carrier protein for transferrin. It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. Low iron concentrations promote increased levels of transferrin receptor, to increase iron intake into the cell. Thus, transferrin receptor maintains cellular iron homeostasis. Expression of human TFR1, but not human TFR2, in hamster cell lines markedly enhanced the infection of viruses pseudotyped with the glycoprotein of Machupo, Guanarito, and Junin viruses, but not with those of Lassa or lymphocytic choriomeningitis viruses. An anti-TFR1 antibody efficiently inhibited the replication of Machupo, Guanarito, Junin, and Sabia viruses, but not that of Lassa virus.TFR1 is a cellular receptor for New World hemorrhagic fever arenaviruses.

分子量

85 kDa

UniProt

P02786

途径

Transition Metal Ion Homeostasis