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MCAM 抗体 (AA 84-189)

This anti-MCAM antibody is a 小鼠 单克隆 antibody detecting MCAM in IHC, WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724898
发货至: 中国

Quick Overview for MCAM 抗体 (AA 84-189) (ABIN1724898)

抗原

See all MCAM 抗体
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

适用

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宿主

  • 108
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  • 1
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小鼠

克隆类型

  • 116
  • 99
单克隆

标记

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This MCAM antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), ELISA

克隆位点

6C3F1
  • 抗原表位

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    AA 84-189

    原理

    MCAM Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wang, Yan: "CD146, a multi-functional molecule beyond adhesion." in: Cancer letters, Vol. 330, Issue 2, pp. 150-62, (2013) (PubMed).

    Jouve, Despoix, Espeli, Gauthier, Cypowyj, Fallague, Schiff, Dignat-George, Vély, Leroyer: "The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells." in: The Journal of biological chemistry, Vol. 288, Issue 4, pp. 2571-9, (2013) (PubMed).

  • 抗原

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    别名

    MCAM

    背景

    The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during
    embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration

    分子量

    71.6 kDa

    基因ID

    4162

    UniProt

    P43121
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