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CD74 抗体 (AA 1-106)

Name: CD74 抗体 (AA 1-106)
Brand: antibodies-online
SKU: ABIN1724871
Availability: OutOfStock

This anti-CD74 antibody is a 小鼠单克隆 antibody detecting CD74 in FACS, WB, ELISA 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Western blot analysis using CD74 mouse mAb against Raji cell lysate. (CD74 抗体 (AA 1-106))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (CD74 抗体 (AA 1-106))

ELISA

Flow cytometric analysis of Jurkat cells using CD74 mouse mAb (green) and negative control (red). (CD74 抗体 (AA 1-106))

FACS

Immunofluorescence analysis of Hela cells using CD74 mouse mAb (green). (CD74 抗体 (AA 1-106))

Western blot analysis using CD74 mAb against human CD74 recombinant protein. (CD74 抗体 (AA 1-106))

Western blot analysis using CD74 mAb against HEK293 (1) and CD74 (AA: 1-106)-hIgGFc transfected HEK293 (2) cell lysate. (CD74 抗体 (AA 1-106))

6 images

(2 references)

产品编号 ABIN1724871

发货至: 中国

Quick Overview for CD74 抗体 (AA 1-106) (ABIN1724871)

抗原

See all CD74 抗体

CD74 (HLA-DR-gamma (CD74))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This CD74 antibody is un-conjugated

应用范围

Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

克隆位点

2D1B3

抗原表位
20

16

15

12

7

7

6

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1
AA 1-106

原理

CD74 Antibody

纯化方法

Purified antibody

免疫原

Purified recombinant fragment of human CD74 (AA: 1-106) expressed in E. Coli.

亚型

IgG1
anti-HLA-DR-gamma (CD74) (AA 78-222) antibody
CD74 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-HLA-DR-gamma (CD74) (AA 64-205) antibody
CD74 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-HLA-DR-gamma (CD74) antibody
CD74 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated

anti-HLA-DR-gamma (CD74) (AA 1-106) antibody
CD74 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 2D1B11 unconjugated

anti-HLA-DR-gamma (CD74) antibody
CD74 适用: 人, 小鼠, Baboon FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal LN-2 unconjugated

anti-HLA-DR-gamma (CD74) (AA 73-232) antibody
CD74 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-HLA-DR-gamma (CD74) antibody
CD74 适用: 人 FACS, WB, IF, IHC, IP, ICC 宿主: 小鼠 Monoclonal PIN-1 unconjugated

anti-HLA-DR-gamma (CD74) (N-Term) antibody
CD74 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-HLA-DR-gamma (CD74) (AA 65-277) antibody
CD74 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-HLA-DR-gamma (CD74) antibody
CD74 适用: 人, 小鼠, Baboon FACS, WB, IHC, StM 宿主: 兔 Monoclonal CLIP-3127R unconjugated Recombinant Antibody

应用备注

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Tian, Zhang, Li, Liu, Dong: "CD74: a potential novel target for triple-negative breast cancer." in: Tumour biology, Vol. 33, Issue 6, pp. 2273-7, (2012) (PubMed).

Zheng, Yang, Rong, Yuan, Ma, Wang, Shen, Cui: "CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer." in: World journal of gastroenterology : WJG, Vol. 18, Issue 18, pp. 2253-61, (2012) (PubMed).
抗原

CD74 (HLA-DR-gamma (CD74))

别名

CD74

背景

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

分子量

33.5 kDa

基因ID

972

UniProt

P04233

途径

Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints