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FLIP 抗体 (AA 100-251)

This anti-FLIP antibody is a 小鼠 单克隆 antibody detecting FLIP in ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724856
发货至: 中国

Quick Overview for FLIP 抗体 (AA 100-251) (ABIN1724856)

抗原

See all FLIP (CFLAR) 抗体
FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

适用

  • 105
  • 69
  • 59
  • 2
  • 2
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  • 1
  • 1

宿主

  • 96
  • 15
  • 2
小鼠

克隆类型

  • 98
  • 15
单克隆

标记

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  • 3
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  • 3
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  • 1
  • 1
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This FLIP antibody is un-conjugated

应用范围

  • 102
  • 39
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  • 26
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  • 14
  • 12
  • 10
  • 9
  • 5
  • 1
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  • 1
ELISA, Immunohistochemistry (IHC)

克隆位点

6G11A6
  • 抗原表位

    • 16
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    • 9
    • 8
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    • 6
    • 4
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    • 2
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-251

    原理

    CFLAR Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Rao-Bindal, Rao, Yu, Kleinerman: "Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts." in: Pediatric blood & cancer, Vol. 60, Issue 4, pp. 575-9, (2013) (PubMed).

    Noh, Lee, Sung, Song, Kim, Woo, Kwon, Lee: "CHOP down-regulates cFLIP(L) expression by promoting ubiquitin/proteasome-mediated cFLIP(L) degradation." in: Journal of cellular biochemistry, Vol. 113, Issue 12, pp. 3692-700, (2012) (PubMed).

  • 抗原

    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

    别名

    CFLAR

    背景

    The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.

    分子量

    55.3 kDa

    基因ID

    8837

    UniProt

    O15519

    途径

    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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