FLIP 抗体 (AA 100-251)
Quick Overview for FLIP 抗体 (AA 100-251) (ABIN1724850)
抗原
See all FLIP (CFLAR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-251
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原理
- CFLAR Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence." in: PLoS ONE, Vol. 7, Issue 9, pp. e44917, (2012) (PubMed).
: "The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition." in: Cancer prevention research (Philadelphia, Pa.), Vol. 5, Issue 4, pp. 612-20, (2012) (PubMed).
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: "Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence." in: PLoS ONE, Vol. 7, Issue 9, pp. e44917, (2012) (PubMed).
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- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
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别名
- CFLAR
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背景
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The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
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分子量
- 55 kDa
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基因ID
- 8837
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UniProt
- O15519
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途径
- Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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