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FLIP 抗体 (AA 100-251)

CFLAR 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A3D12 unconjugated
产品编号 ABIN1724850
发货至: 中国
  • 抗原 See all FLIP (CFLAR) 抗体
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    抗原表位
    • 15
    • 15
    • 14
    • 9
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-251
    适用
    • 96
    • 61
    • 54
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 84
    • 14
    • 2
    小鼠
    克隆类型
    • 86
    • 14
    单克隆
    标记
    • 48
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLIP antibody is un-conjugated
    应用范围
    • 89
    • 37
    • 27
    • 24
    • 19
    • 18
    • 15
    • 11
    • 10
    • 10
    • 9
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    CFLAR Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. Coli.
    克隆位点
    7A3D12
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Bedolla, Gong, Prihoda, Yeh, Thompson, Ghosh, Kumar: "Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence." in: PLoS ONE, Vol. 7, Issue 9, pp. e44917, (2012) (PubMed).

    Li, Ren, Yue, Chen, Khuri, Sun: "The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition." in: Cancer prevention research (Philadelphia, Pa.), Vol. 5, Issue 4, pp. 612-20, (2012) (PubMed).

  • 抗原
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    别名
    CFLAR (CFLAR 产品)
    背景
    The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.


    分子量
    55 kDa
    基因ID
    8837
    UniProt
    O15519
    途径
    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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