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CD33 抗体 (AA 15-237)

Name: CD33 抗体 (AA 15-237)
Brand: antibodies-online
SKU: ABIN1724812
Availability: OutOfStock

This anti-CD33 antibody is a 小鼠单克隆 antibody detecting CD33 in FACS, ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Western blot analysis using CD33 mAb against human CD33 recombinant protein. (CD33 抗体 (AA 15-237))

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using CD33 mouse mAb with DAB staining. (CD33 抗体 (AA 15-237))

IHC

Western blot analysis using CD33 mouse mAb against THP-1 (1) cell lysate. (CD33 抗体 (AA 15-237))

Western blot analysis using CD33 mAb against HEK293 (1) and CD33 (AA: 15-237)-hIgGFc transfected HEK293 (2) cell lysate. (CD33 抗体 (AA 15-237))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (CD33 抗体 (AA 15-237))

ELISA

Flow cytometric analysis of HeLa cells using CD33 mouse mAb (green) and negative control (purple). (CD33 抗体 (AA 15-237))

FACS

Immunohistochemical analysis of paraffin-embedded endometrium tissues using CD33 mouse mAb with DAB staining. (CD33 抗体 (AA 15-237))

IHC

7 images

(2 references)

产品编号 ABIN1724812

发货至: 中国

Quick Overview for CD33 抗体 (AA 15-237) (ABIN1724812)

抗原

See all CD33 抗体

CD33

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This CD33 antibody is un-conjugated

应用范围

Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)

克隆位点

2C6B7

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抗原表位
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1

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AA 15-237

原理

CD33 Antibody

纯化方法

Ascitic fluid

免疫原

Purified recombinant fragment of human CD33 (AA: 15-237) expressed in E. Coli.

亚型

IgG1
anti-CD33 (CD33) (AA 101-200) antibody
CD33 适用: 人, 小鼠 FACS, WB, ELISA, IHC (fro), ICC, IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD33 (CD33) (AA 15-237) antibody
CD33 适用: 人 FACS, WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2C6B7 unconjugated

anti-CD33 (CD33) (AA 18-240) antibody
CD33 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD33 (CD33) (AA 49-259) antibody
CD33 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD33 (CD33) (AA 261-364) antibody
CD33 适用: 人 FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD33 (CD33) (AA 1-364) antibody
CD33 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D12-G4 unconjugated

anti-CD33 (CD33) antibody
CD33 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD33 (CD33) antibody
CD33 适用: 人, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, Func, MS 宿主: 小鼠 Monoclonal WM53 unconjugated

anti-CD33 (CD33) antibody
CD33 适用: 人, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, MS 宿主: 小鼠 Monoclonal WM53 unconjugated

anti-CD33 (CD33) (AA 18-269) antibody
CD33 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM77 unconjugated

应用备注

ELISA: 1/10000
FCM: 1/200 - 1/400

限制

仅限研究用
状态

Liquid

缓冲液

Ascitic fluid containing 0.03 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Deng, Liu, Wang, Tang, Ren, Xu, Ma, Wang, Zhuang, Wang, Chen: "The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease." in: Human genetics, Vol. 131, Issue 7, pp. 1245-9, (2012) (PubMed).

Schubert, Kellner, Stein, Kügler, Schwenkert, Saul, Mentz, Singer, Stockmeyer, Hillen, Mackensen, Fey: "A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting." in: mAbs, Vol. 3, Issue 1, pp. 21-30, (2011) (PubMed).
抗原

CD33

别名

CD33

背景

The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD)

分子量

39.8 kDa

基因ID

945

UniProt

P20138