ALDH2 抗体 (AA 317-517)
(2 references)Quick Overview for ALDH2 抗体 (AA 317-517) (ABIN1724795)
抗原
See all ALDH2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 317-517
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原理
- ALDH2 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human ALDH2 (AA: 317-517) expressed in E. Coli.
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亚型
- IgG1
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anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) (AA 1-380) antibody
ALDH2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) (Center) antibodyALDH2 适用: 人, 小鼠 WB, ELISA, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) (AA 408-517) antibodyALDH2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E5 unconjugated
anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) (AA 317-517) antibodyALDH2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) (N-Term) antibodyALDH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) (Internal Region) antibodyVerified ALDH2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibodyALDH2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 138CT22-3-8 unconjugated
anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibodyALDH2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 8C8 unconjugated
anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibodyALDH2 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 3F10 unconjugated Recombinant Antibody
anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) (AA 1-517) antibodyALDH2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/150
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease." in: European heart journal, Vol. 33, Issue 13, pp. 1606-14, (2012) (PubMed).
: "The acute effects of ethanol and acetaldehyde on physiological responses after ethanol ingestion in young healthy men with different ALDH2 genotypes." in: Clinical toxicology (Philadelphia, Pa.), Vol. 50, Issue 4, pp. 242-9, (2012) (PubMed).
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: "Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease." in: European heart journal, Vol. 33, Issue 13, pp. 1606-14, (2012) (PubMed).
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- ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
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别名
- ALDH2
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背景
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This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 56.3 kDa
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基因ID
- 217
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UniProt
- P05091
抗原
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