NEUROD1 抗体 (AA 26-91)
Quick Overview for NEUROD1 抗体 (AA 26-91) (ABIN1724757)
抗原
See all NEUROD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 26-91
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原理
- Neurod Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human Neurod (AA: 26-91 ) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The neuronal differentiation factor NeuroD1 downregulates the neuronal repellent factor Slit2 expression and promotes cell motility and tumor formation of neuroblastoma." in: Cancer research, Vol. 71, Issue 8, pp. 2938-48, (2011) (PubMed).
: "Neurogenic differentiation 1 directs differentiation of cytokeratin 19-positive human pancreatic nonendocrine cells into insulin-producing cells." in: Transplantation proceedings, Vol. 42, Issue 6, pp. 2071-4, (2010) (PubMed).
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The neuronal differentiation factor NeuroD1 downregulates the neuronal repellent factor Slit2 expression and promotes cell motility and tumor formation of neuroblastoma." in: Cancer research, Vol. 71, Issue 8, pp. 2938-48, (2011) (PubMed).
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- NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
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别名
- Neurod
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背景
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This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
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分子量
- 40 kDa
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UniProt
- Q13562
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途径
- Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
抗原
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