PRDM1 抗体
Quick Overview for PRDM1 抗体 (ABIN1724737)
抗原
See all PRDM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PRDM1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human PRDM1 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Transcription factors Xbp-1, Blimp-1, and BSAP are involved in the regulation of plasmacytic differentiation induced by 2-methoxyestradiol in myeloma cell lines." in: International journal of hematology, Vol. 86, Issue 5, pp. 429-37, (2008) (PubMed).
: "Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. ..." in: Nature genetics, Vol. 40, Issue 8, pp. 955-62, (2008) (PubMed).
: "Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells." in: Nature cell biology, Vol. 8, Issue 6, pp. 623-30, (2006) (PubMed).
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: "Transcription factors Xbp-1, Blimp-1, and BSAP are involved in the regulation of plasmacytic differentiation induced by 2-methoxyestradiol in myeloma cell lines." in: International journal of hematology, Vol. 86, Issue 5, pp. 429-37, (2008) (PubMed).
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- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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别名
- PRDM1
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背景
- PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
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分子量
- 88 kDa
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基因ID
- 639
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UniProt
- O75626
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途径
- Regulation of Muscle Cell Differentiation
抗原
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