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ZBTB7B 抗体

This anti-ZBTB7B antibody is a 小鼠 单克隆 antibody detecting ZBTB7B in WB, ELISA, IHC 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724728
发货至: 中国

Quick Overview for ZBTB7B 抗体 (ABIN1724728)

抗原

See all ZBTB7B 抗体
ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

适用

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宿主

  • 24
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小鼠

克隆类型

  • 26
  • 5
单克隆

标记

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This ZBTB7B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

7C12
  • 原理

    ZBTB7B Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human ZBTB7B expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Egawa: "Runx and ThPOK: a balancing act to regulate thymocyte lineage commitment." in: Journal of cellular biochemistry, Vol. 107, Issue 6, pp. 1037-45, (2009) (PubMed).

    Ghayor, Herrouin, Chadjichristos, Ala-Kokko, Takigawa, Pujol, Galéra: "Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration." in: The Journal of biological chemistry, Vol. 275, Issue 35, pp. 27421-38, (2000) (PubMed).

  • 抗原

    ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

    别名

    ZBTB7B

    背景

    ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

    分子量

    58 kDa

    UniProt

    O15156
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