F2RL3 抗体 (AA 1-330)
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北京 101111
Quick Overview for F2RL3 抗体 (AA 1-330) (ABIN1724706)
抗原
See all F2RL3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-330
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原理
- PAR4 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli.
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亚型
- IgG1
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anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (AA 320-343) antibody
F2RL3 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (AA 48-385) antibodyF2RL3 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (AA 136-150), (C149S), (Extracellular) antibodyKO Validated F2RL3 适用: 人 WB, IHC, IF, FACS, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (AA 18-82) antibodyF2RL3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F4 unconjugated
anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (Extracellular Domain) antibodyF2RL3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (Cytoplasmic Domain) antibodyF2RL3 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (AA 136-150), (C149S), (Extracellular) antibody (FITC)KO Validated F2RL3 适用: 人 FACS, LCI 宿主: 兔 Polyclonal FITC
anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (cleaved), (N-Term) antibodyF2RL3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (Internal Region) antibodyF2RL3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) (AA 20-150) antibodyF2RL3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence." in: Psychiatric genetics, Vol. 16, Issue 5, pp. 193-6, (2006) (PubMed).
: "Phosphorylation of Par-4 by protein kinase A is critical for apoptosis." in: Molecular and cellular biology, Vol. 25, Issue 3, pp. 1146-61, (2005) (PubMed).
: "Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28266-75, (2004) (PubMed).
: "Prostate apoptosis response gene-4 (par-4) abrogates the survival function of p185(BCR-ABL) in hematopoietic cells." in: Experimental hematology, Vol. 32, Issue 7, pp. 649-56, (2004) (PubMed).
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: "No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence." in: Psychiatric genetics, Vol. 16, Issue 5, pp. 193-6, (2006) (PubMed).
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- F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
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别名
- PAR4
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背景
- Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.
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UniProt
- Q96IZ0
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途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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