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F2RL3 抗体 (AA 1-330)

This anti-F2RL3 antibody is a 小鼠 单克隆 antibody detecting F2RL3 in WB, ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1724706
发货至: 中国

Quick Overview for F2RL3 抗体 (AA 1-330) (ABIN1724706)

抗原

See all F2RL3 抗体
F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))

适用

  • 58
  • 32
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  • 1
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  • 1

宿主

  • 55
  • 5
小鼠

克隆类型

  • 55
  • 5
单克隆

标记

  • 31
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  • 2
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  • 1
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  • 1
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This F2RL3 antibody is un-conjugated

应用范围

  • 46
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

3G9H7
  • 抗原表位

    • 15
    • 3
    • 3
    • 3
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    • 3
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    • 2
    • 2
    • 2
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    • 1
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    • 1
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    • 1
    AA 1-330

    原理

    PAR4 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Weller, Dahl, Lohoff, Kampman, Oslin, Dackis, Ferraro, OBrien, Berrettini: "No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence." in: Psychiatric genetics, Vol. 16, Issue 5, pp. 193-6, (2006) (PubMed).

    Gurumurthy, Goswami, Vasudevan, Rangnekar: "Phosphorylation of Par-4 by protein kinase A is critical for apoptosis." in: Molecular and cellular biology, Vol. 25, Issue 3, pp. 1146-61, (2005) (PubMed).

    Xie, Guo: "Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28266-75, (2004) (PubMed).

    Kukoc-Zivojnov, Puccetti, Chow, Bergmann, Ruthardt, Hoelzer, Mitrou, Weidmann, Boehrer: "Prostate apoptosis response gene-4 (par-4) abrogates the survival function of p185(BCR-ABL) in hematopoietic cells." in: Experimental hematology, Vol. 32, Issue 7, pp. 649-56, (2004) (PubMed).

  • 抗原

    F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))

    别名

    PAR4

    背景

    Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.

    UniProt

    Q96IZ0

    途径

    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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