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PTK2B 抗体 (AA 815-997)

Name: PTK2B 抗体 (AA 815-997)
Brand: antibodies-online
SKU: ABIN1724705
Availability: OutOfStock

This anti-PTK2B antibody is a 小鼠单克隆 antibody detecting PTK2B in WB, IHC 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 3+ publications.

Western blot analysis using PYK2 mouse mAb against Raji (1), PMA induced THP-1 (2), Jurkat (3) and Ramos (4) cell lysate. (PTK2B 抗体 (AA 815-997))

Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using PYK2 mouse mAb. (PTK2B 抗体 (AA 815-997))

IHC

2 images

(3 references)

产品编号 ABIN1724705

发货至: 中国

Quick Overview for PTK2B 抗体 (AA 815-997) (ABIN1724705)

抗原

See all PTK2B 抗体

PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This PTK2B antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

5E2D5

Discover our top product PTK2B Primary Antibody

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AA 815-997

原理

PYK2 Antibody

纯化方法

Ascitic fluid

免疫原

Purified recombinant fragment of PYK2 (aa815-997) expressed in E. Coli.

亚型

IgG2a
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibody
PTK2B 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 1-1009) antibody
PTK2B 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 682-871) antibody
PTK2B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1F9 unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibody
PTK2B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) antibody
PTK2B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 805-838), (C-Term) antibody
PTK2B 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB50594 unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 812-861) antibody
PTK2B 适用: 人, 小鼠, 大鼠, 犬, 兔, Pig, 马, 猴, Cow, 豚鼠, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 682-871) antibody
PTK2B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal X1 unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (Tyr579) antibody
PTK2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 707-875) antibody
PTK2B 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA: 1/10000

限制

仅限研究用
状态

Liquid

缓冲液

Ascitic fluid containing 0.03 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Dylla, Deyle, Theunissen, Padurean, Verfaillie: "Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products." in: Experimental hematology, Vol. 32, Issue 4, pp. 365-74, (2004) (PubMed).

Haglund, Ivankovic-Dikic, Shimokawa, Kruh, Dikic: "Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites." in: Journal of cell science, Vol. 117, Issue Pt 12, pp. 2557-68, (2004) (PubMed).

van der Horst, Weber, Ullrich: "Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma." in: International journal of cancer. Journal international du cancer, Vol. 113, Issue 5, pp. 689-98, (2004) (PubMed).
抗原

PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

别名

PYK2

背景

PYK2: PTK2B protein tyrosine kinase 2 beta, also known as PTK2B, PKB, PTK, CAKB, FAK2, FRNK. Entrez Protein NP_004094. It is a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

分子量

115.8 kDa

基因ID

2185

NCBI登录号

NP_004094

UniProt

Q14289

途径

EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling