TYRO3 抗体 (AA 138-321)
Quick Overview for TYRO3 抗体 (AA 138-321) (ABIN1724702)
抗原
See all TYRO3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 138-321
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原理
- Tyro3 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of Tyro3 (aa138-321) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The Ran binding protein RanBPM interacts with Axl and Sky receptor tyrosine kinases." in: The international journal of biochemistry & cell biology, Vol. 37, Issue 11, pp. 2344-56, (2005) (PubMed).
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: "The Ran binding protein RanBPM interacts with Axl and Sky receptor tyrosine kinases." in: The international journal of biochemistry & cell biology, Vol. 37, Issue 11, pp. 2344-56, (2005) (PubMed).
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- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
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别名
- Tyro3
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背景
- Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98 kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.
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UniProt
- Q06418
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途径
- RTK signaling
抗原
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