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MSH6 抗体

This anti-MSH6 antibody is a 小鼠 单克隆 antibody detecting MSH6 in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724694
发货至: 中国

Quick Overview for MSH6 抗体 (ABIN1724694)

抗原

See all MSH6 抗体
MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

适用

  • 141
  • 36
  • 29
  • 8
  • 3
  • 2
  • 1
  • 1
  • 1

宿主

  • 77
  • 61
  • 3
小鼠

克隆类型

  • 93
  • 47
  • 1
单克隆

标记

  • 61
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  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MSH6 antibody is un-conjugated

应用范围

  • 97
  • 80
  • 53
  • 50
  • 29
  • 18
  • 14
  • 13
  • 11
  • 11
  • 8
  • 6
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  • 1
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  • 1
ELISA

克隆位点

3A10H7
  • 原理

    MSH6 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of MSH6 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Hess, Mendillo, Mazur, Kolodner: "Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 3, pp. 558-63, (2006) (PubMed).

    Lynch, Lynch: "What the physician needs to know about Lynch syndrome: an update." in: Oncology (Williston Park, N.Y.), Vol. 19, Issue 4, pp. 455-63; discussion 463-4, 466, 469, (2005) (PubMed).

  • 抗原

    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

    别名

    MSH6

    背景

    Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.

    基因ID

    2956

    UniProt

    P52701

    途径

    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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