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APOA1 抗体

This anti-APOA1 antibody is a 小鼠 单克隆 antibody detecting APOA1 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724693
发货至: 中国

Quick Overview for APOA1 抗体 (ABIN1724693)

抗原

See all APOA1 抗体
APOA1 (Apolipoprotein A-I (APOA1))

适用

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宿主

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小鼠

克隆类型

  • 139
  • 89
单克隆

标记

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This APOA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

5F4F5
  • 原理

    APOA1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human APOA1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Brown, Rea, Hamon, Hixson, Boerwinkle, Clark, Sing: "The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability." in: Journal of molecular medicine (Berlin, Germany), Vol. 84, Issue 7, pp. 561-72, (2006) (PubMed).

    Martina, Benso, Gigliardi, Masha, Origlia, Granata, Ghigo: "Short-term dehydroepiandrosterone treatment increases platelet cGMP production in elderly male subjects." in: Clinical endocrinology, Vol. 64, Issue 3, pp. 260-4, (2006) (PubMed).

  • 抗原

    APOA1 (Apolipoprotein A-I (APOA1))

    别名

    APOA1

    背景

    APOA1: apolipoprotein A-I, it is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.

    分子量

    25 kDa

    基因ID

    335

    UniProt

    P02647

    途径

    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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