APOA1 抗体
Quick Overview for APOA1 抗体 (ABIN1724693)
抗原
See all APOA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- APOA1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human APOA1 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability." in: Journal of molecular medicine (Berlin, Germany), Vol. 84, Issue 7, pp. 561-72, (2006) (PubMed).
: "Short-term dehydroepiandrosterone treatment increases platelet cGMP production in elderly male subjects." in: Clinical endocrinology, Vol. 64, Issue 3, pp. 260-4, (2006) (PubMed).
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The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability." in: Journal of molecular medicine (Berlin, Germany), Vol. 84, Issue 7, pp. 561-72, (2006) (PubMed).
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- APOA1 (Apolipoprotein A-I (APOA1))
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别名
- APOA1
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背景
- APOA1: apolipoprotein A-I, it is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.
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分子量
- 25 kDa
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基因ID
- 335
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UniProt
- P02647
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途径
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
抗原
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