IL-10 抗体
Quick Overview for IL-10 抗体 (ABIN1724633)
抗原
See all IL-10 (IL10) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- IL-10 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human IL-10 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- IL-10 (IL10) (Interleukin 10 (IL10))
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别名
- IL-10
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背景
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Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by
lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-
regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on
macrophages. It also enhances B cell survival, proliferation, and antibody production. This
cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling
pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. -
基因ID
- 3586
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UniProt
- P22301
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
抗原
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