Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only : WB1 μg/mL ELISA1-10 μg/mL IHC1-10 μg/mL IP1-10 μg/mL
Positive control: HeLa cells
限制
仅限研究用
缓冲液
PBS, pH 7.4
注意事项
Dilute in PBS or medium which is identical to that used in the assay system.
储存条件
4 °C/-20 °C
储存方法
Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
有效期
6 months
抗原
Hsc70 (HSPA8)
(Heat Shock 70kDa Protein 8 (HSPA8))
别名
Hsc70 (Hsp73)
背景
Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
Heat shock cognate 71 kDa protein Heat shock 70 kDa protein 8 Lipopolysaccharide-associated protein 1, LAP-1, LPS-associated protein 1 Gene name: HSPA8, HSC70, HSP73, HSPA10