GRP78 抗体
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北京 101111
Quick Overview for GRP78 抗体 (ABIN1721537)
抗原
See all GRP78 (HSPA5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reacts with human GRP78. Cross-reacts with mouse, rat, bovine, hamster, rabbit, monkey, xenopus and fungi (Cryphonectria parasitica) protein.
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纯化方法
- Purified (protein G)
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免疫原
- His-tagged human GRP78 (accession no. NP_001156906.1)
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亚型
- IgG1
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anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody
HSPA5 适用: 大鼠 WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (Internal Region) antibodyHSPA5 适用: 人, 大鼠, 小鼠 WB, ICC, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (AA 550-650) antibodyHSPA5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (AA 251-360) antibodyHSPA5 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (PE)HSPA5 适用: 大鼠 WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal PE
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (FITC)HSPA5 适用: 大鼠 WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal FITC
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (APC)HSPA5 适用: 大鼠 WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal APC
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (HRP)HSPA5 适用: 大鼠 WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal HRP
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (Atto 594)HSPA5 适用: 大鼠 WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 594
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (Atto 488)HSPA5 适用: 大鼠 WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 488
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB(0.5 - 1.0 μg/mL)
Positive control: HeLa cell -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2 mg/mL
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缓冲液
- PBS, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Dilute in PBS or medium which is identical to that used in the assay system.
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储存条件
- -20 °C
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储存方法
- For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
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有效期
- 6 months
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- GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
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别名
- GRP78
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背景
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Categorized as stress response proteins, BiPs play an important role in folding and assembly of nascent proteins and in scavenging of misfolded proteins in the endoplasmic reticulum lumen. Translation of BiP is directed by an internal ribosomal entry site (IRES) in the 5- nontranslated region of BiP mRNA. BiP IRES activity increases when cells are heat-stressed. GRP78 is also important in maintenance of cell homeostasis and the prevention of apoptosis. Levels of GRP78 protein are reduced in brains of Alzheimer's disease patients.
78 kDa glucose-regulated protein, GRP-78 Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78 Heat shock 70 kDa protein 5 Immunoglobulin heavy chain-binding protein, BiP Gene name: HSPA5, GRP78 -
基因ID
- 3309
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UniProt
- P11021
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途径
- Thyroid Hormone Synthesis, ER-Nucleus Signaling
抗原
-
