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GRP78 抗体

HSPA5 适用: 人, 大鼠, 小鼠, Frog, 非洲爪蟾, 哺乳动物 WB, ELISA 宿主: 小鼠 Monoclonal 6H4-2G7 unconjugated
产品编号 ABIN1721537
发货至: 中国
  • 抗原 See all GRP78 (HSPA5) 抗体
    GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
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    人, 大鼠, 小鼠, Frog, 非洲爪蟾, 哺乳动物
    宿主
    • 127
    • 88
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    小鼠
    克隆类型
    • 132
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    单克隆
    标记
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    This GRP78 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    特异性
    Reacts with human GRP78. Cross-reacts with mouse, rat, bovine, hamster, rabbit, monkey, xenopus and fungi (Cryphonectria parasitica) protein.
    纯化方法
    Purified (protein G)
    免疫原
    His-tagged human GRP78 (accession no. NP_001156906.1)
    克隆位点
    6H4-2G7
    亚型
    IgG1
    Top Product
    Discover our top product HSPA5 Primary Antibody
  • 应用备注
    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    WB(0.5 - 1.0 μg/mL)

    Positive control: HeLa cell
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    PBS, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Dilute in PBS or medium which is identical to that used in the assay system.
    储存条件
    -20 °C
    储存方法
    For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
    有效期
    6 months
  • 抗原
    GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
    别名
    GRP78 (HSPA5 产品)
    别名
    GRP78 antibody, BiP antibody, GRP-78 antibody, grp78 antibody, hspa5a antibody, BIP antibody, MIF2 antibody, AL022860 antibody, AU019543 antibody, Bip antibody, D2Wsu141e antibody, D2Wsu17e antibody, Grp78 antibody, Hsce70 antibody, SEZ-7 antibody, Sez7 antibody, baffled antibody, mBiP antibody, cb865 antibody, fb60h09 antibody, fi36d04 antibody, wu:fb60h09 antibody, wu:fi36d04 antibody, zgc:55994 antibody, zgc:77606 antibody, 78 kDa glucose-regulated protein antibody, heat shock protein family A (Hsp70) member 5 antibody, BiP/GRP78 antibody, glucose-regulated protein 78 antibody, putative glucose-regulated protein 78 antibody, Hsp70 family ATPase KAR2 antibody, heat shock protein family A (Hsp70) member 5 S homeolog antibody, heat shock 70 kDa protein 5a antibody, heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) antibody, heat shock protein 5 antibody, heat shock protein family A member 5 antibody, CpipJ_CPIJ003550 antibody, HSPA5 antibody, grp78 antibody, LOC100533358 antibody, BiP/grp78 antibody, Tc00.1047053506585.40 antibody, Tb11.02.5450 antibody, Tb11.02.5500 antibody, LMJF_28_1200 antibody, KAR2 antibody, LOC100135840 antibody, hspa5.S antibody, hspa5 antibody, Hspa5 antibody
    背景
    Categorized as stress response proteins, BiPs play an important role in folding and assembly of nascent proteins and in scavenging of misfolded proteins in the endoplasmic reticulum lumen. Translation of BiP is directed by an internal ribosomal entry site (IRES) in the 5- nontranslated region of BiP mRNA. BiP IRES activity increases when cells are heat-stressed. GRP78 is also important in maintenance of cell homeostasis and the prevention of apoptosis. Levels of GRP78 protein are reduced in brains of Alzheimer's disease patients.

    78 kDa glucose-regulated protein, GRP-78 Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78 Heat shock 70 kDa protein 5 Immunoglobulin heavy chain-binding protein, BiP Gene name: HSPA5, GRP78
    基因ID
    3309
    UniProt
    P11021
    途径
    Thyroid Hormone Synthesis, ER-Nucleus Signaling
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