CASP14 抗体 (AA 155-242)
Quick Overview for CASP14 抗体 (AA 155-242) (ABIN1714934)
抗原
See all CASP14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 155-242
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Pig,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Caspase 14
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亚型
- IgG
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anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 133-242) antibody
CASP14 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C9 unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 223-242) antibodyCASP14 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (C-Term) antibodyCASP14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 17-248) antibodyCASP14 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-242) antibodyCASP14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 171-230) antibodyCASP14 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-246) antibodyCASP14 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-242) antibodyCASP14 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 59-93) antibodyCASP14 适用: 人 WB 宿主: 兔 Polyclonal RB52885 unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-242) antibodyCASP14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
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别名
- Caspase 14
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背景
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Synonyms: Caspase-14, CASP-14, CASP14
Background: Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum (PubMed:15556625). Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity). In vitro has a preference for the substate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF (PubMed:16854378, PubMed:19960512). Involved in processing of prosaposin in the epidermis (By similarity). May be involved in retinal pigment epithelium cell barrier function (PubMed:25121097). Involved in DNA degradation in differentiated keratinocytes probably by cleaving DFFA/ICAD leading to liberation of DFFB/CAD (PubMed:24743736).
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基因ID
- 23581
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UniProt
- P31944
抗原
-
