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FKBP8 抗体 (AA 311-412)

This anti-FKBP8 antibody is a 兔 多克隆 antibody detecting FKBP8 in WB, ELISA, ICC, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1714762
发货至: 中国

Quick Overview for FKBP8 抗体 (AA 311-412) (ABIN1714762)

抗原

See all FKBP8 抗体
FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

适用

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宿主

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克隆类型

  • 61
  • 8
多克隆

标记

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This FKBP8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 311-412

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FKBP38/FKBP8

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

    别名

    FKBP38/FKBP8

    背景

    Synonyms: 38 kDa FK 506 binding protein homolog, 38 kDa FK506-binding protein, 38 kDa FKBP, 38 kDa, FK506 binding protein 8, FK506 binding protein 8, 38 kDa, FK506 binding protein, 38 kDa, FK506-binding protein 8, FKBP 38, FKBP-38, FKBP-8, FKBP8, FKBP8_HUMAN, FKBPR38, hFKBP38, Peptidyl-prolyl cis-trans isomerase FKBP8, PPIase FKBP8, Rotamase, Sam11.

    Background: FKBP8 is an immunophilin family member lacking PPIase/arotamase activity that influences immunoregulation, protein folding and trafficking in neurons associated with memory function. The FKBPr38 form derives from a truncated ORF. Presenilin 1 and 2 form molecular complexes withnd promote degradation of_KBPr38, and Bcl-2, and sequester these proteins in ER/Golgi, thereby inhibiting FKBPr38-mediated, ?secretase-independent, mitochondrial targeting of Bcl-2. FKBP8 present in the central nervous system can antagonize hedgehog (HH) signaling, where HH is critical for patterning and growth of many tissues in the developing embryo. Mouse FKBPr38 mRNA is present in neurons and glial cells and appears more pronounced in neurons associated with the hippocampal formation in adult mouse brains.

    基因ID

    23770

    途径

    Autophagy
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