Caspase 6 抗体 (AA 181-293)
Quick Overview for Caspase 6 抗体 (AA 181-293) (ABIN1714708)
抗原
See all Caspase 6 (CASP6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-293
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交叉反应
- Drosophila melanogaster, 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Caspase-6 subunit p11
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
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别名
- Caspase-6
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背景
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Synonyms: Caspase-6 subunit p11, Caspase-6 p11, Apoptosis Related Cysteine Protease, Apoptotic cysteine protease MCH2, Apoptotic protease MCH 2, Apoptotic protease MCH2, Casp 6, Casp6, Caspase 6 apoptosis related cysteine protease, Caspase 6 precursor, Caspase6, Human cysteine protease Mch2 isoform alpha, Mch 2, Mch2, CASP6_HUMAN.
Background: Caspase-6 Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit is compose of heterodimer of a18 kDa (p18) and a 11 kDa (p11) subunit. Subcellular location at cytoplasmic. Cleavages by CPP32, caspase-8 or -10 generate the two active subunits. It belongs to the peptidase C14 family.
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基因ID
- 839
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UniProt
- P55212
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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