GFI1 抗体 (AA 301-400)
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北京 101111
Quick Overview for GFI1 抗体 (AA 301-400) (ABIN1714623)
抗原
See all GFI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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交叉反应
- 小鼠, 大鼠, 非洲爪蟾
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预测反应
- Human,Dog,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GFI1/ZNF163
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亚型
- IgG
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anti-Growth Factor Independent 1 (GFI1) (AA 1-91) antibody
GFI1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Growth Factor Independent 1 (GFI1) antibodyGFI1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) antibodyGFI1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D7 unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 1-91) antibodyGFI1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 280-330) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 1-422) antibodyGFI1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 32-81) antibodyGFI1 适用: 人, 大鼠, Cow, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- GFI1 (Growth Factor Independent 1 (GFI1))
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别名
- GFI1/ZNF163
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背景
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Synonyms: GFI 1, GFI1, GFI-1, GFI1_HUMAN, Growth factor independence 1, growth factor independent 1, Growth factor independent protein 1, SCN2, Zinc finger protein 163, Zinc finger protein Gfi 1, Zinc finger protein Gfi-1, Zinc finger protein Gfi1, ZNF 163, ZNF163.
Background: Growth factor independent 1 (Gfi-1) is a transcriptional repressor that specifically binds to the DNA consensus sequence TAAATCAC(A/T)GCA. The carboxy-terminus of Gfi-1 contains six C2H2-type zinc finger motifs, and zinc fingers 3, 4 and 5 are required for the binding of Gfi-1 to its DNA binding site. Gfi-1 also contains a 20 amino acid SNAG domain which mediates transcriptional repression. It represses Bax at the mRNA and protein levels, resulting in the inhibition of cell death. Gfi1 is expressed outside the lymphoid system in granulocytes and activated macrophages. Gfi-1B, a related protein, is a transcriptional repressor primarily expressed in bone marrow and spleen. Gfi-1B is a direct repressor of the p21 promoter and the Socs 1 and 3 promoters. The genes encoding human Gfi-1 and Gfi-1B map to chromosome 1p22 and 9q34.3, respectively.
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基因ID
- 2672
抗原
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