APC2 抗体 (AA 1-100)
Quick Overview for APC2 抗体 (AA 1-100) (ABIN1714590)
抗原
See all APC2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-100
-
预测反应
- Human,Mouse,Rat,Dog,Pig,Horse
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human APCL/APC2
-
亚型
- IgG
-
-
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 2041-2181) antibody
APC2 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3A2G2 unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 849-898) antibodyAPC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 2011-2221) antibodyAPC2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 122-152) antibodyAPC2 适用: 人 WB 宿主: 兔 Polyclonal RB53935 unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (Middle Region) antibodyAPC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
-
别名
- APCL/APC2
-
背景
-
Synonyms: Adenomatous polyposis coli protein 2, Adenomatous polyposis coli protein-like, APCL, APC2_HUMAN.
Background: The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner?s syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion. APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin. Interactions between cytoskeleton and the APC, E cadherin, b/g catenin complex are mediated by a-catenin.
-
基因ID
- 10297
-
途径
- WNT signaling
抗原
-
