CTLA4 抗体 (AA 75-170)
Quick Overview for CTLA4 抗体 (AA 75-170) (ABIN1714514)
抗原
See all CTLA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-170
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Sheep,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CTLA-4/CD152
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma. ..." in: Oncoimmunology, Vol. 5, Issue 5, pp. e1100789, (2016) (PubMed).
: "Histamine suppresses regulatory T cells mediated by TGF-? in murine chronic allergic contact dermatitis." in: Experimental dermatology, Vol. 24, Issue 4, pp. 280-4, (2015) (PubMed).
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: "Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma. ..." in: Oncoimmunology, Vol. 5, Issue 5, pp. e1100789, (2016) (PubMed).
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- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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别名
- CTLA4
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背景
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Synonyms: CD, GSE, GRD4, CD152, CTLA-4, IDDM12, CELIAC3, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA4
Background: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
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基因ID
- 1493
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UniProt
- P16410
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途径
- Cancer Immune Checkpoints
抗原
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