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AIRE 抗体 (AA 51-150)

Name: AIRE 抗体 (AA 51-150)
SKU: ABIN1714476
Availability: OutOfStock

This anti-AIRE antibody is a 兔多克隆 antibody detecting AIRE in ELISA, ICC, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人.

产品编号 ABIN1714476

发货至: 中国

Quick Overview for AIRE 抗体 (AA 51-150) (ABIN1714476)

抗原

See all AIRE 抗体

AIRE (Autoimmune Regulator (AIRE))

适用

人

宿主

兔

克隆类型

多克隆

标记

This AIRE antibody is un-conjugated

应用范围

ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product AIRE Primary Antibody

抗原表位
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AA 51-150

预测反应

Human,Mouse,Rat,Dog,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human AIRE

亚型

IgG
anti-Autoimmune Regulator (AIRE) (C-Term) antibody
Verified AIRE 适用: 人 WB, ELISA, IF, IHC, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Autoimmune Regulator (AIRE) (AA 30-130) antibody
AIRE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Autoimmune Regulator (AIRE) (N-Term) antibody
AIRE 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Autoimmune Regulator (AIRE) (Internal Region) antibody
Verified AIRE 适用: 人, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Autoimmune Regulator (AIRE) (Internal Region) antibody
AIRE 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Autoimmune Regulator (AIRE) (AA 39-108) antibody
AIRE 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated

anti-Autoimmune Regulator (AIRE) (pSer156) antibody
AIRE 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Autoimmune Regulator (AIRE) (N-Term) antibody
AIRE 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Autoimmune Regulator (AIRE) (AA 76-125) antibody
AIRE 适用: 人, 马, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Autoimmune Regulator (AIRE) (Internal Region) antibody
Verified AIRE 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

应用备注

ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

AIRE (Autoimmune Regulator (AIRE))

别名

AIRE

背景

Synonyms: AIRE-1, AIRE, AIRE_HUMAN, AIRE1, APECED, APECED protein, APS1, APSI, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator, Autoimmune regulator protein, PGA1.
Background: The autoimmune regulator gene, which is defective in the hereditary auto-immune disease APECED, encodes the transcriptional activator AIRE. AIRE is expressed in the medullary epithelial cells and monocyte-dendritic cells of the thymus, with lower expression in the spleen, fetal liver and lymph nodes. In adult tissue, AIRE expression in the thymus is confined to the medulla and the cortico-medullary junction, where it is modulated by thymocytes undergoing negative selection. At the cellular level, AIRE is located in microtubular structures of the cyto-skeleton and in discrete nuclear dots resembling ND10 nuclear bodies. AIRE is induced by developing early thymocytes and is associated with the correct establishment of a regular thymic environment. AIRE regulates thymic architecture via transcriptional control of downstream target genes. AIRE mutations in APECED patients may affect thymic T cell selection and the formation of self-tolerance.

基因ID

326

途径

Chromatin Binding