我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

EIF2A 抗体 (pSer52)

Name: EIF2A 抗体 (pSer52)
SKU: ABIN1714407
Availability: OutOfStock

Cited in 3+ publications. This 兔多克隆 anti-EIF2A antibody specifically detects EIF2A in WB, ELISA, FACS, IHC (p), IF (p), IF (cc) 和 IHC (fro). The antibody is reactive with 人, 小鼠和大鼠 samples.

Paraformaldehyde-fixed, paraffin embedded rat lung tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-eIF2 alpha (Ser51) Polyclonal Antibody, Unconjugated at 1:500 overnight at 4°C, followed by a conjugated secondary and DAB staining (EIF2A 抗体 (pSer52))

IHC (p)

1 image

(3 references)

产品编号 ABIN1714407

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EIF2A 抗体 (pSer52) (ABIN1714407)

抗原

See all EIF2A 抗体

EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This EIF2A antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product EIF2A Primary Antibody

抗原表位
18

16

8

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
pSer52

交叉反应

人, 小鼠, 大鼠

预测反应

Cow

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human eIF2 alpha subunit 1 around the phosphorylation site of Ser52 [EL(p-S)RR]

亚型

IgG
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 448-576) antibody
EIF2A 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3A7B11 unconjugated

anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 448-576) antibody
EIF2A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A7A8 unconjugated

anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) antibody
EIF2A 适用: 人, 小鼠, 大鼠, 猴 WB, IF, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) antibody
EIF2A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) antibody
KD Validated EIF2A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4195 unconjugated Recombinant Antibody

anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (pSer51) antibody
KD Validated EIF2A 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB3905 unconjugated Recombinant Antibody

anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 437-465) antibody
EIF2A 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) antibody
EIF2A 适用: 人, 小鼠, 大鼠, 猴 WB, IF, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 1-100) antibody
EIF2A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D5 unconjugated

anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (Center) antibody
EIF2A 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Cha, Song, Kang, Park, Park, Kim, Shim, Kim: "miR-211 Plays a Critical Role in Cnidium officinale Makino Extract-Induced, ROS/ER Stress-Mediated Apoptosis in U937 and U266 Cells." in: International journal of molecular sciences, Vol. 19, Issue 3, (2018) (PubMed).

Yao, Lu, Hu, Yu, Chen, Wang: "A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure." in: Nature communications, Vol. 8, Issue 1, pp. 133, (2017) (PubMed).

He, Long, Zhong, Fu, Li, Lin: "Sustained endoplasmic reticulum stress inhibits hepatocyte proliferation via downregulation of c-Met expression." in: Molecular and cellular biochemistry, Vol. 389, Issue 1-2, pp. 151-8, (2014) (PubMed).
抗原

EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

别名

eIF2 alpha

背景

Synonyms: EIF2, EIF-2, EIF2A, EIF-2A, EIF-2alpha, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, EIF2S1
Background: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 4S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 6S ribosomal subunit to form the 8S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

基因ID

1965

UniProt

P05198

途径

Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly