GUCA1B 抗体 (AA 21-120)
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北京 101111
Quick Overview for GUCA1B 抗体 (AA 21-120) (ABIN1714375)
抗原
See all GUCA1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GCAP2
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亚型
- IgG
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anti-Guanylate Cyclase Activator 1B (Retina) (GUCA1B) antibody
GUCA1B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase Activator 1B (Retina) (GUCA1B) (AA 29-57), (N-Term) antibodyGUCA1B 适用: 人 WB 宿主: 兔 Polyclonal RB40485 unconjugated
anti-Guanylate Cyclase Activator 1B (Retina) (GUCA1B) (AA 93-200) antibodyGUCA1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E7 unconjugated
anti-Guanylate Cyclase Activator 1B (Retina) (GUCA1B) (AA 34-83) antibodyGUCA1B 适用: 人, 小鼠, Cow, 犬, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase Activator 1B (Retina) (GUCA1B) (N-Term) antibodyGUCA1B 适用: 人, 小鼠, Cow, 犬, 兔, 大鼠, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- GUCA1B (Guanylate Cyclase Activator 1B (Retina) (GUCA1B))
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别名
- GCAP2
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背景
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Synonyms: GCAP 2, Guanylate Cyclase Activating Protein Photoreceptor 2, Guanylate Cyclase Activator 1B, Guanylin 2, Guanylyl cyclase-activating protein 2, GUC1B_HUMAN, GUCA 2, GUCA1B.
Background: The intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of cGMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90 % similar, consisting of 201 to 205 amino acids and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event. The genes which encode GCAP1 and GCAP2 map to human chromosome 6p21.1.
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基因ID
- 2979
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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