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GUCA1B 抗体 (N-Term)

GUCA1B 适用: 人 WB 宿主: 兔 Polyclonal RB40485 unconjugated
产品编号 ABIN1881399
发货至: 中国
  • 抗原 See all GUCA1B 抗体
    GUCA1B (Guanylate Cyclase Activator 1B (Retina) (GUCA1B))
    抗原表位
    • 13
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 29-57, N-Term
    适用
    • 26
    • 11
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 26
    • 1
    克隆类型
    • 26
    • 1
    多克隆
    标记
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GUCA1B antibody is un-conjugated
    应用范围
    • 20
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This GUCA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human GUCA1B.
    克隆位点
    RB40485
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Sato, Nakazawa, Usui, Tanimoto, Abe, Ohguro: "Mutations in the gene coding for guanylate cyclase-activating protein 2 (GUCA1B gene) in patients with autosomal dominant retinal dystrophies." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 243, Issue 3, pp. 235-42, (2005) (PubMed).

    Nishiguchi, Sokal, Yang, Roychowdhury, Palczewski, Berson, Dryja, Baehr: "A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration." in: Investigative ophthalmology & visual science, Vol. 45, Issue 11, pp. 3863-70, (2004) (PubMed).

    Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

  • 抗原
    GUCA1B (Guanylate Cyclase Activator 1B (Retina) (GUCA1B))
    别名
    GUCA1B (GUCA1B 产品)
    别名
    GUCA1B antibody, BC018258 antibody, GCAP2 antibody, GUCA2 antibody, RP48 antibody, guanylate cyclase activator 1B antibody, guanylate cyclase activator 1B (retina) antibody, GUCA1B antibody, guca1b antibody, Guca1b antibody
    背景
    The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq].
    分子量
    23420
    NCBI登录号
    NP_002089
    UniProt
    Q9UMX6
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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