FZD3 抗体 (AA 121-220)
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北京 101111
Quick Overview for FZD3 抗体 (AA 121-220) (ABIN1714171)
抗原
See all FZD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-220
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FZD3/Frizzled 3
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亚型
- IgG
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anti-Frizzled Family Receptor 3 (FZD3) (AA 23-205) antibody
FZD3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 3 (FZD3) (Internal Region) antibodyFZD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 3 (FZD3) (N-Term) antibodyFZD3 适用: 人, 小鼠, 大鼠, Bat, Cow, 犬, Hamster, 马, 猴, Pig, 兔, 小鸡 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 3 (FZD3) (AA 55-157) antibodyFZD3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2H5 unconjugated
anti-Frizzled Family Receptor 3 (FZD3) (AA 55-157) antibodyFZD3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-Frizzled Family Receptor 3 (FZD3) (Internal Region) antibodyFZD3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 3 (FZD3) (AA 55-157) antibodyFZD3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Frizzled Family Receptor 3 (FZD3) (AA 581-596), (Intracellular) antibodyFZD3 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 3 (FZD3) (AA 481-530) antibodyFZD3 适用: 人, 小鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 3 (FZD3) (Internal Region) antibodyFZD3 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Deregulation of the planar cell polarity genes CELSR3 and FZD3 in Hirschsprung disease." in: Experimental and molecular pathology, Vol. 101, Issue 2, pp. 241-248, (2016) (PubMed).
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: "Deregulation of the planar cell polarity genes CELSR3 and FZD3 in Hirschsprung disease." in: Experimental and molecular pathology, Vol. 101, Issue 2, pp. 241-248, (2016) (PubMed).
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- FZD3 (Frizzled Family Receptor 3 (FZD3))
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别名
- FZD3/Frizzled 3
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背景
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Synonyms: Fz-3, Frizzled-3, hFz3, FZD3
Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
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基因ID
- 7976
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UniProt
- Q9NPG1
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途径
- WNT signaling, Tube Formation
抗原
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